Usagi Tsukino is an average student and crybaby klutz who constantly scores low on her tests. Unexpectedly, her humdrum life is turned upside down when she saves a cat with a crescent moon on its head from danger. The cat, named Luna, later reveals that their meeting was not an accident: Usagi is destined to become Sailor Moon, a planetary guardian with the power to protect the Earth. Given a special brooch that allows her to transform, she must use her new powers to save the city from evil energy-stealing monsters sent by the malevolent Queen Beryl of the Dark Kingdom. But getting accustomed to her powers and fighting villains are not the only things she has to worry about. She must find the lost princess of the Moon Kingdom, the other Sailor Guardians, and the Legendary Silver Crystal in order to save the planet from destruction.

Usagi Tsukino and her friends have been living peacefully until they are called into action again as Sailor Guardians, planetary warriors fighting for the peace of the galaxy. Usagi, also known as Sailor Moon, leads their group into battle when a new threat from beyond the stars presents itself: two survivors of an alien race, An and Ail. In order to save the source of their life force, the Makai Tree, An and Ail begin harvesting energy from unsuspecting humans. The Sailor Guardians must stop their plot or face the annihilation of Earth. But as one threat subsides, another follows—this time in the form of a little girl from the future who seeks the source of Sailor Moon's power to save her family. However, she is not the only one vying for it, as a group known as the Black Moon Clan also wishes to obtain the power and use it for nefarious purposes. In order to protect their destinies and the harmony of the universe, Sailor Moon and the rest of the Sailor Guardians must fight to stop these forces from succeeding.

In ancient times, a group of young men devoted their lives to protecting Athena, the Goddess of Wisdom and War. These men were capable of fighting without weapons—a swing of their fist alone was powerful enough to rip the very sky apart and shatter the earth beneath them. These brave heroes became known as Saints, as they could summon up the power of the Cosmos from within themselves. Now, in present day, a new generation of Saints is about to come forth. The young and spirited Seiya is fighting a tough battle for the Sacred Armor of Pegasus, and he isn't about to let anyone get in the way of him and his prize. Six years of hard work and training pay off with his victory and new title as one of Athena's Saints. But Seiya's endeavor doesn't end there. In fact, plenty of perils and dangerous enemies face him and the rest of the Saints throughout the series. What new quests await the heroes of the epic Saint Seiya saga?