The anime's story follows Tsubasa, a new hire in the A&R department of the major recording company Gandala Music. Tsubasa is immediately assigned to oversee the idol unit B-PROJECT, which is made up of three idol groups: Kitakore, THRIVE, and MooNs. This is Tsubasa's first job, and she gets involved in various incidents and accidents as she deals with this group of young men who each have their own differing personalities. (Source: ANN)

High school biology teacher Tetsuo Takahashi may look like your average everyday instructor, but beneath his gentle appearance lies something less ordinary: his fascination for the Ajin, more commonly known as Demi. Although these half-human, half-monster beings have integrated into human society, Takahashi believes that much about them will remain unknown unless he interacts with them firsthand. Demi-chan wa Kataritai follows Takahashi's daily life in Shibasaki High School together with his three Demi students—Hikari Takanashi, an energetic vampire; Kyouko Machi, a gentle dullahan; and Yuki Kusakabe, the shy snow woman. Along the way, Takahashi also meets fellow teacher Sakie Satou, a succubus with an aversion towards men. To fulfill his goal of learning more about the Demi, Takahashi decides to conduct casual interviews with the girls to learn more about their abilities, psyche, and interaction with human society. As Takahashi strengthens his bond with his students, he soon discovers that the Demi are not as unusual as he initially believed.

After unknowingly participating in a kidnapping, college student Yuuya Nomoto finds his friends brutally murdered by Hitomi Uzaki, the high school girl they attempted to abduct. Forced to drive her to an undisclosed location, he finds himself being wagered as the prize for a death match between two Therianthropes, superpowered human-animal hybrids created through advanced gene therapy. As one of these hybrids, Hitomi uses the speed and fearlessness she gained from her ratel genes to viciously dispatch her foe and save Yuuya from certain death. Waking up hours later hoping the whole event was only a nightmare, Yuuya realizes that he has become embroiled in a secret proxy war between four large Japanese business conglomerates, with the winner taking control of the economy. As her sole albeit unwilling investor, his life is now directly linked to Hitomi's ability to participate in underground bloodsport matches known only as Killing Bites.

People fall in love in the most mysterious of ways. This statement seems to be especially true for the affluent genius playboy Ryou Amakusa. When he nearly falls off the stairs one rainy morning, a girl named Ichika Arima saves him. As if by fate, Ryou encounters Ichika again later that night; she happens to be the best friend of his little sister, Rio. Wanting to thank her, Ryou attempts to woo Ichika by employing his usual flirtatious tactics only to be immediately shot down, his target creeped out by his behavior. Rather than being discouraged, Ryou instead becomes more enthralled by her, and he begins to do everything he can to steal Ichika's heart despite receiving disgusted reactions each time. However, as time passes by, will Ichika remain repulsed by Ryou's creepy yet dedicated advances?