That jumbled piece of architecture, that cacophony of hissing steam and creaking joints, with smoke billowing from it as it moves on its own... That castle is home to the magnificent wizard Howl, infamous for both his magical prowess and for being a womanizer—or so the rumor goes in Sophie Hatter's small town. Sophie, as the plain daughter of a hatmaker, does not expect much from her future and is content with working hard in the shop. However, Sophie's simple life takes a turn for the exciting when she is ensnared in a disturbing situation, and the mysterious wizard appears to rescue her. Unfortunately, this encounter, brief as it may be, spurs the vain and vengeful Witch of the Waste—in a fit of jealousy caused by a past discord with Howl—to put a curse on the maiden, turning her into an old woman. In an endeavor to return to normal, Sophie must accompany Howl and a myriad of eccentric companions—ranging from a powerful fire demon to a hopping scarecrow—in his living castle, on a dangerous adventure as a raging war tears their kingdom apart.

Ichirou Inuyashiki is a 58-year-old family man who is going through a difficult time in his life. Though his frequent back problems are painful, nothing hurts quite as much as the indifference and distaste that his wife and children have for him. Despite this, Ichirou still manages to find solace in Hanako, an abandoned Shiba Inu that he adopts into his home. However, his life takes a turn for the worse when a follow-up physical examination reveals that Ichirou has stomach cancer and only three months to live; though he tries to be strong, his family's disinterest causes an emotional breakdown. Running off into a nearby field, Ichirou embraces his dog and weeps—until he notices a strange figure standing before him. Suddenly, a bright light appears and Ichirou is enveloped by smoke and dust. When he comes to, he discovers something is amiss—he has been reborn as a mechanized weapon wearing the skin of his former self. Though initially shocked, the compassionate Ichirou immediately uses his newfound powers to save a life, an act of kindness that fills him with happiness and newfound hope. However, the origins of these strange powers remain unclear. Who was the mysterious figure at the site of the explosion, and are they as kind as Ichirou when it comes to using this dangerous gift?

In a world filled with planes and airships, Sheeta is a young girl who has been kidnapped by government agents who seek her mysterious crystal amulet. While trapped aboard an airship, she finds herself without hope—that is, until the ship is raided by pirates. Taking advantage of the ensuing confusion, Sheeta manages to flee from her captors. Upon her escape, she meets Pazu, a boy who dreams of reaching the fabled flying castle, Laputa. The two decide to embark on a journey together to discover this castle in the sky. However, they soon find the government agents back on their trail, as they too are trying to reach Laputa for their own greedy purposes. Tenkuu no Shiro Laputa follows the soaring adventures of Sheeta and Pazu, all while they learn how dreams and dire circumstances can bring two people closer together.

A millennium has passed since the catastrophic nuclear war named the Seven Days of Fire, which destroyed nearly all life on Earth. Humanity now lives in a constant struggle against the treacherous jungle that has evolved in response to the destruction caused by mankind. Filled with poisonous spores and enormous insects, the jungle spreads rapidly across the Earth and threatens to swallow the remnants of the human race. Away from the jungle exists a peaceful farming kingdom known as the Valley of the Wind, whose placement by the sea frees it from the spread of the jungle's deadly toxins. The Valley's charismatic young princess, Nausicaä, finds her tranquil kingdom disturbed when an airship from the kingdom of Tolmekia crashes violently in the Valley. After Nausicaä and the citizens of the Valley find a sinister pulsating object in the wreckage, the Valley is suddenly invaded by the Tolmekian military, who intend to revive a dangerous weapon from the Seven Days of Fire. Now Nausicaä must fight to stop the Tolmekians from plunging the Earth into a cataclysm which humanity could never survive, while also protecting the Valley from the encroaching forces of the toxic jungle.