At the renowned Shuchiin Academy, Miyuki Shirogane and Kaguya Shinomiya are the student body's top representatives. Ranked the top student in the nation and respected by peers and mentors alike, Miyuki serves as the student council president. Alongside him, the vice president Kaguya—eldest daughter of the wealthy Shinomiya family—excels in every field imaginable. They are the envy of the entire student body, regarded as the perfect couple. However, despite both having already developed feelings for the other, neither are willing to admit them. The first to confess loses, will be looked down upon, and will be considered the lesser. With their honor and pride at stake, Miyuki and Kaguya are both equally determined to be the one to emerge victorious on the battlefield of love!

The Four Cardinal Heroes are a group of ordinary men from modern-day Japan summoned to the kingdom of Melromarc to become its saviors. Melromarc is a country plagued by the Waves of Catastrophe that have repeatedly ravaged the land and brought disaster to its citizens for centuries. The four heroes are respectively bestowed a sword, spear, bow, and shield to vanquish these Waves. Naofumi Iwatani, an otaku, becomes cursed with the fate of being the Shield Hero. Armed with only a measly shield, Naofumi is belittled and ridiculed by his fellow heroes and the kingdom's people due to his weak offensive capabilities and lackluster personality. When the heroes are provided with resources and comrades to train with, Naofumi sets out with the only person willing to train alongside him, Malty Melromarc. He is soon betrayed by her, however, and becomes falsely accused of taking advantage of her. Naofumi then becomes heavily discriminated against and hated by the people of Melromarc for something he didn't do. With a raging storm of hurt and mistrust in his heart, Naofumi begins his journey of strengthening himself and his reputation. Further along however, the difficulty of being on his own sets in, so Naofumi buys a demi-human slave on the verge of death named Raphtalia to accompany him on his travels. As the Waves approach the kingdom, Naofumi and Raphtalia must fight for the survival of the kingdom and protect the people of Melromarc from their ill-fated future.

It happened suddenly: The dead began to rise and Japan was thrown into total chaos. As these monsters begin terrorizing a high school, Takashi Kimuro is forced to kill his best friend when he gets bitten and joins the ranks of the walking dead. Vowing to protect Rei Miyamoto, the girlfriend of the man he just executed, they narrowly escape their death trap of a school, only to be greeted with a society that has already fallen. Soon, Takashi and Rei band together with other students on a journey to find their family members and uncover what caused this overwhelming pandemic. Joining them is Saeko Busujima, the beautiful president of the Kendo Club; Kouta Hirano, an otaku with a fetish for firearms; Saya Takagi, the daughter of an influential politician; and Shizuka Marikawa, their hot school nurse. But will the combined strength of these individuals be enough to conquer this undead apocalypse?

Unlike many schools, attending Hyakkaou Private Academy prepares students for their time in the real world. Since many of the students are the children of the richest people in the world, the academy has its quirks that separate it from all the others. By day, it is a normal school, educating its pupils in history, languages, and the like. But at night, it turns into a gambling den, educating them in the art of dealing with money and manipulating people. Money is power; those who come out on top in the games stand at the top of the school. Yumeko Jabami, a seemingly naive and beautiful transfer student, is ready to try her hand at Hyakkaou's special curriculum. Unlike the rest, she doesn't play to win, but for the thrill of the gamble, and her borderline insane way of gambling might just bring too many new cards to the table.