In the distant future, humanity has been driven to near-extinction by giant beasts known as Klaxosaurs, forcing the surviving humans to take refuge in massive fortress cities called Plantations. Children raised here are trained to pilot giant mechas known as FranXX—the only weapons known to be effective against the Klaxosaurs—in boy-girl pairs. Bred for the sole purpose of piloting these machines, these children know nothing of the outside world and are only able to prove their existence by defending their race. Hiro, an aspiring FranXX pilot, has lost his motivation and self-confidence after failing an aptitude test. Skipping out on his class' graduation ceremony, Hiro retreats to a forest lake, where he encounters a mysterious girl with two horns growing out of her head. She introduces herself by her codename Zero Two, which is known to belong to an infamous FranXX pilot known as the Partner Killer. Before Hiro can digest the encounter, the Plantation is rocked by a sudden Klaxosaur attack. Zero Two engages the creature in her FranXX, but it is heavily damaged in the skirmish and crashes near Hiro. Finding her partner dead, Zero Two invites Hiro to pilot the mecha with her, and the duo easily defeats the Klaxosaur in the ensuing fight. With a new partner by his side, Hiro has been given a chance at redemption for his past failures, but at what cost?

It happened suddenly: The dead began to rise and Japan was thrown into total chaos. As these monsters begin terrorizing a high school, Takashi Kimuro is forced to kill his best friend when he gets bitten and joins the ranks of the walking dead. Vowing to protect Rei Miyamoto, the girlfriend of the man he just executed, they narrowly escape their death trap of a school, only to be greeted with a society that has already fallen. Soon, Takashi and Rei band together with other students on a journey to find their family members and uncover what caused this overwhelming pandemic. Joining them is Saeko Busujima, the beautiful president of the Kendo Club; Kouta Hirano, an otaku with a fetish for firearms; Saya Takagi, the daughter of an influential politician; and Shizuka Marikawa, their hot school nurse. But will the combined strength of these individuals be enough to conquer this undead apocalypse?

With the appearance of a mysterious virus that kills everyone above the age of 13, mankind becomes enslaved by previously hidden, power-hungry vampires who emerge in order to subjugate society with the promise of protecting the survivors, in exchange for donations of their blood. Among these survivors are Yuuichirou and Mikaela Hyakuya, two young boys who are taken captive from an orphanage, along with other children whom they consider family. Discontent with being treated like livestock under the vampires' cruel reign, Mikaela hatches a rebellious escape plan that is ultimately doomed to fail. The only survivor to come out on the other side is Yuuichirou, who is found by the Moon Demon Company, a military unit dedicated to exterminating the vampires in Japan. Many years later, now a member of the Japanese Imperial Demon Army, Yuuichirou is determined to take revenge on the creatures that slaughtered his family, but at what cost? Owari no Seraph is a post-apocalyptic supernatural shounen anime that follows a young man's search for retribution, all the while battling for friendship and loyalty against seemingly impossible odds.

On December 24, 2029—the day colloquially known as the Lost Christmas—the Apocalypse Virus spread across Japan, bringing death to its citizens and plunging the country into utter chaos. In an effort to establish order, the United Nations sends the GHQ to assist with the crisis by containing the outbreak while removing all political autonomy in the process. A decade later, the country still lives under their control, unable to break free from their draconian rule. Frustrated with the state of the nation, a resistance group named the Funeral Parlor aims to liberate Japan from the GHQ. Led by the charismatic Gai Tsutsugami, the group plots to steal a vial containing the Void Genome to further their goals. The vial falls into the hands of internet vocalist Inori Yuzuriha, who ends up being hunted by the GHQ's Anti-Bodies forces. Having nowhere to go, she seeks refuge in a warehouse where she meets Shuu Ouma—a socially awkward high school student who is a huge fan of her music. Shuu gets dragged into the conflict the moment he rescues Inori, and the Void Genome shatters in his hand, granting him the Power of the Kings. While learning how to control his grand new ability, Shuu must now fight to liberate Japan from its cruel oppressors.