Striking fear into the hearts of mortals, the Demon Lord Satan begins to conquer the land of Ente Isla with his vast demon armies. However, while embarking on this brutal quest to take over the continent, his efforts are foiled by the hero Emilia, forcing Satan to make his swift retreat through a dimensional portal only to land in the human world. Along with his loyal general Alsiel, the demon finds himself stranded in modern-day Tokyo and vows to return and complete his subjugation of Ente Isla—that is, if they can find a way back! Powerless in a world without magic, Satan assumes the guise of a human named Sadao Maou and begins working at MgRonald's—a local fast-food restaurant—to make ends meet. He soon realizes that his goal of conquering Ente Isla is just not enough as he grows determined to climb the corporate ladder and become the ruler of Earth, one satisfied customer at a time! Whether it's part-time work, household chores, or simply trying to pay the rent on time, Hataraku Maou-sama! presents a hilarious view of the most mundane aspects of everyday life, all through the eyes of a hapless demon lord.

Misaki Ayuzawa is a unique phenomenon within Seika High School. In a predominantly male institution, she became the first-ever female student council president through her honesty and diligence. Ever since Misaki got promoted to the position, she has been working tirelessly to ensure a better school life for all girls. Despite that, Misaki is very strict with the boys, which has earned her the title Demon President. One day, after hearing a girl cry in the hallway, Misaki encounters Takumi Usui—the most popular boy in the school—as he rejects a love confession. Enraged at what she is seeing, Misaki reprimands him for making the girl cry. However, Usui is indifferent and brushes it off as nothing. Unexpectedly, Misaki soon runs into Usui again, but this time when she is working at a maid cafe! Embarrassed that someone has found out about her secret occupation, Misaki promises herself not to let Usui destroy her reputation. However, the mysterious boy now begins to visit the same cafe regularly to observe and tease Misaki. When push comes to shove, will Usui still be able to keep the president's secret?

Tokyo is currently experiencing rain showers that seem to disrupt the usual pace of everyone living there to no end. Amidst this seemingly eternal downpour arrives the runaway high school student Hodaka Morishima, who struggles to financially support himself—ending up with a job at a small-time publisher. At the same time, the orphaned Hina Amano also strives to find work to sustain herself and her younger brother. Both fates intertwine when Hodaka attempts to rescue Hina from shady men, deciding to run away together. Subsequently, Hodaka discovers that Hina has a strange yet astounding power: the ability to call out the sun whenever she prays for it. With Tokyo's unusual weather in mind, Hodaka sees the potential of this ability. He suggests that Hina should become a sunshine girl—someone who will clear the sky for people when they need it the most. Things begin looking up for them at first. However, it is common knowledge that power always comes with a hefty price...

Wishing to be independent, 16-year-old Maika Sakuranomiya is desperate to nail down a part-time job so that she can afford to study abroad. Unfortunately, her applications are constantly rejected due to the menacing look she unintentionally makes whenever she smiles, despite her otherwise cheerful disposition. After yet another failed interview, she chances upon Café Stile, a coffee shop where the servers interact with the customers while roleplaying distinctive characteristics. The Italian store manager, Dino, becomes infatuated with Maika's cuteness at first sight, and offers her a job as a waitress with a sadistic nature. Coupled with her inherent clumsiness, she successfully manages to serve a pair of masochistic customers in accordance with her new, ruthless persona. Alongside Kaho Hinata as the tsundere and Mafuyu Hoshikawa as the younger sister, Maika decides to make the most out of her unique quirk and cements her position in the cafe with merciless cruelty!