A goldfish sneaks away from home and floats off on the back of a jellyfish. After getting stuck in a glass jar, she drifts to the shore where she is freed by Sousuke, a five-year-old boy who lives with his mother Lisa in a house by the sea while his father Koichi works on a fishing boat. After healing a cut on Sousuke's finger by licking it, the goldfish is named Ponyo by her new friend. Unknown to Sousuke, Ponyo already has a name and a family. Her father Fujimoto, a sorcerer who forsook his humanity to live underwater, searches frantically for his daughter Brunhilde. When found and captured, Ponyo rejects her birth name and declares that she wants to become a human. Using the power received from Sousuke's blood, she grows arms and legs and escapes to the surface once more. But the magic released into the ocean causes an imbalance in nature, causing the Moon to start falling out of orbit and the tides to grow dangerously stronger. Reunited with Ponyo, Sousuke must pass an ancient test to restore order in the world and let his companion live on as a human.

After an enthusiastic invitation from her friend, Kaede Honjou reluctantly agrees to try New World Online: a very popular VRMMO played by thousands of people across Japan. Naming her in-game character Maple, she sets out on her journey. As a complete novice to such games, she allocates all of her stat points into vitality, desiring to not get hurt. With not a single point in any other stat, Maple has extraordinarily high defense, but she can't move quickly or hit hard. This does not end badly for her, however. Due to her high defense, Maple acquires overpowered skills such as Total Defense, Poison Immunity, and Devour. These skills, along with the incredibly powerful items she obtains, allow her to obliterate most enemies in a single hit. After only a few days of playing the game, Maple claims third place in a server-wide event, gaining a reputation as a player who is both unkillable and absurdly powerful. Despite her overpowered character, Kaede has much to learn. As she progresses through the game, she meets new friends and acquaintances, helping her complete new levels and events. Through all of her adventures, she may even pick up some other crazy skills that exceed all expectations.

Despite the immediate challenges following becoming a devil hunter with the Public Safety Bureau, Denji has quickly adapted to his new life and responsibilities. As the chaos of Denji's first ordeal with Public Safety settles down, the elite devil hunter Makima decides to take Denji out on a date. Although the date strengthens his affection for Makima and he swears to not fall in love with anyone else, Denji soon finds himself in a tricky situation when he meets a seemingly innocent cafe worker named Reze. With her forward and flirty demeanor, Reze immediately captures Denji's heart, driving him to frequent the cafe where she works and deepen his relationship with her. However, Denji is completely oblivious to the fact that meeting Reze might have grave consequences beyond simply deciding which woman his heart belongs to.

Kintarou Ooe is a specialist in part-time work, riding all over the highways and byways of Japan on his trusty steed, the Mikazuki 5, and finding employment wherever he can. His adventures bring him knowledge and experience that can't be taught in a classroom, from political corruption to the delicacy of a young woman's heart. With nothing but the open road before him—not to mention the many beautiful women along the way—Kintarou pursues his spirit of education while attempting to hold down his various odd jobs, however undignified they may be. As he learns from each task he takes on, who knows what could happen? He might even be able to save the world one day. One thing is for sure—this will all be very educational!