The devastation of the Mugen Train incident still weighs heavily on the members of the Demon Slayer Corps. Despite being given time to recover, life must go on, as the wicked never sleep: a vicious demon is terrorizing the alluring women of the Yoshiwara Entertainment District. The Sound Hashira, Tengen Uzui, and his three wives are on the case. However, when he soon loses contact with his spouses, Tengen fears the worst and enlists the help of Tanjirou Kamado, Zenitsu Agatsuma, and Inosuke Hashibira to infiltrate the district's most prominent houses and locate the depraved Upper Rank Demon.

Haruto Kirishima lived a calm life out in the countryside, away from the fast-paced life of the city. Then Yuzuki Eba appeared in his life out of nowhere, having come from Tokyo to briefly live with her family. Their time together left him enamored with the memories of that short period before she just as abruptly disappeared from his life, and left him full of questions. Kimi no Iru Machi begins some time later, after Haruto moves to Tokyo to live with his sister, in order to pursue a career as a cook. In reality though he wishes to be with Yuzuki. Things don't start good though. When he arrives he is mistaken for a burglar and attacked by his sister's neighbour Mishima Asuka. After the misunderstanding is cleared his feelings begin to waver though. Is Eba, who keeps avoiding him for seemingly no reason, the one for him or is it Asuka?

The aloof protagonist: a bookworm who is deeply detached from the world he resides in. He has no interest in others and is firmly convinced that nobody has any interest in him either. His story begins when he stumbles across a handwritten book, titled Living with Dying. He soon identifies it as a secret diary belonging to his popular, bubbly classmate Sakura Yamauchi. She then confides in him about the pancreatic disease she is suffering from and that her time left is finite. Only her family knows about her terminal illness; not even her best friends are aware. Despite this revelation, he shows zero sympathy for her plight, but caught in the waves of Sakura's persistent buoyancy, he eventually concedes to accompanying her for her remaining days. As the pair of polar opposites interact, their connection strengthens, interweaving through their choices made with each passing day. Her apparent nonchalance and unpredictability disrupts the protagonist's impassive flow of life, gradually opening his heart as he discovers and embraces the true meaning of living.

The limited-edition of the 26th manga volume will include an anime adaptation of the popular special flashback chapter Uchi ga Kita Machi (The Town Where I Arrived). The story reveals how Haruto, Akari, and Takashi first met during childhood, and serves as a prologue to the TV anime. The 27th limited-edition manga volume will include a special anime episode produced in full cooperation with Seo Kouji. This OVA will be the animation of the end of the manga. (Volume 27 is the final volume of the long-running series.)