Throughout history, humans have been at odds with Beastmen—a species capable of changing shape due to their genetic Beast Factor. Because of this conflict, Beastmen have been forced into hiding. Anima City serves as a safe haven for these oppressed individuals to live free from human interference. During a festival celebrating the town's 10th anniversary, Michiru Kagemori, a human who suddenly turned into a tanuki, finds that Anima City is a far cry from paradise. After witnessing an explosion in the square, she is confronted by Shirou Ogami, a seemingly indestructible wolf and sworn protector of all Beastmen. As they pursue the criminals behind the bombing, the two discover that Michiru is anything but an ordinary Beastman, and look to investigate her mysterious past and uncanny abilities. Could she turn out to be the missing link between Humans and Beastmen?

Second-year high school student Yatora Yaguchi is a delinquent with excellent grades, but is unmotivated to find his true calling in life. Yatora spends his days working hard to maintain his academic standing while hanging out with his equally unambitious friends. However, beneath his carefree demeanor, Yatora does not enjoy either activity and wishes he could find something more fulfilling. While mulling over his predicament, Yatora finds himself staring at a vibrant landscape of Shibuya. Unable to express how he feels about the unusually breathtaking sight, he picks up a paintbrush, hoping his thoughts will be conveyed on canvas. After receiving praise for his work, the joy he feels sends him on a journey to enter the extremely competitive Tokyo University of the Arts—a school that only accepts one in every two hundred applicants. Facing talented peers, a lack of understanding of the fine arts, and struggles to obtain his parents’ approval, Yatora is confronted by much adversity. In the hopes of securing one of the five prestigious spots in his program of choice, Yatora must show that his inexperience does not define him.

A world where it has been established that people routinely swing between slightly different parallel worlds... Koyomi Takasaki, who lives with his mother following his parents' divorce, enrolls in a local university prep school. Due to the atmosphere concentrated on studies and his social awkwardness, Koyomi is unable to make friends. One day, he is suddenly approached by his classmate Kazune Takigawa, who tells him that she has travelled from the 85th world where she and Koyomi are lovers. (Source: MAL News)

Momiji is an average girl until the day she finds she is the descendant of the great Kushinada family. Only she, with her Kushinada blood, can stop the Aragami, demonic plant-like monsters threatening to destroy Japan. Along to help her is the TAC, and a possible love interest in a young man named Kusanagi. (Source: ANN)