There is no putting it lightly—Tsunayoshi Sawada is just no good. He is clumsy, talentless, and desperately in love with the school idol Kyouko Sasagawa, a girl so completely out of his league. Dubbed Loser Tsuna by his classmates, he seems to be the very personification of failure in the guise of a middle-schooler. Tsuna's boring life takes an extraordinary twist when he encounters the mysterious Reborn, who happens to be a hitman... and shockingly, a baby! Sent from the strongest Mafia family in Italy, Reborn is assigned the daunting mission of preparing the dull middle schooler to succeed the ninth boss of the notorious Vongola family, who is on the brink of retirement. The dull boy has a grueling road ahead, but with the help of his new criminal affiliates and his peculiar home tutor, perhaps even Loser Tsuna can achieve greatness.

With the initiation of the Patrian civil war came the creation of half-beast, half-human soldiers—a development of the outnumbered Northerners in a desperate attempt to counter the overwhelming Southern forces. Able to quickly dominate battlefields and achieve victory with ease, the soldiers' godlike abilities earned them the name Incarnates. However, as the war raged on, the Incarnates encountered a problem involving the beasts inside them that they were unable to rectify by ordinary means. Once the war was over, mysteries and accounts of the Incarnates submitting to the misfortune of their war days surfaced. Aware of the horrors they faced during the war, Special Sergeant Major and former captain of the Incarnates Hank Henriette becomes a Beast Hunter—those who take the lives of Incarnates who have succumbed to the issues they experienced on the battlefields. After witnessing her father, a former Incarnate soldier, meet his end at the hands of one such Beast Hunter, Nancy Schaal Bancroft resolves to hunt the man who took her father's life. However, Nancy's eye-opening encounter with the Beast Hunter influences her to instead seek the reason behind her father's death and the Incarnates' problematic existence in society.

Hazumu was a shy boy who enjoyed gardening, collecting herbs, and long walks in the mountains. One day he finally worked up the courage to confess his love to Yasuna, but she rejected him. Depressed, he wandered up Mt. Kashimayama, the place where they first met, to reconsider his feelings. After getting lost, he wished upon a shooting star and received a bizarre twist of fate. Now he is a she, and she stumbles headfirst back into social life and relationships only to find that the entire landscape has changed! (Source: Media Blasters)

Katsu Kaizou is a very gullible, 17-year-old high school student and a believer in science fiction, aliens, ghosts, UFOs, conspiracies, etc. He thinks that everything going on around him is the result of some sort of alien plot to take over the world. Each story is pretty much self-contained and is completely bizarre. Kaizou joins the school's science club, makes new friends, and ends up coming in contact with all sorts of strange things like log people, deadly sushi, pee-blades, scary infections, robot invasions, ghosts, living dolls, and more!