The energetic Tapio Chatarozawa and the cool-headed Kuehiko Roshihara are two young cats trying out various part-time jobs. From delivering packages to washing windows on skyscrapers, the pair explore the opportunities that await them out on the recruiting field. As they struggle to learn the ropes, the duo endures the antics of their colorful customers and supervisors while bonding as working buddies.

For the regular cells of the human body, life consists of countless repetitive tasks. They spend every day multiplying, leaving little time for other activities. But one day, this monotony is abruptly interrupted by a cell with an odd-looking hat. Tired of unending drudgery, another cell named Ippan Saibou decides to join this quirky stranger for a day of pranks, jokes, and mischief.

The once-feared Demon Lord Satan of Ente Isla, who had to flee to Earth after being defeated by the hero Emilia Justinia, is now leading a peaceful life in Tokyo under the alias Sadao Maou. Having become a model employee of a local fast-food restaurant, Sadao has to provide for his former generals Alciel and Lucifer who joined him in Japan, as well as avoid confrontations with Emi Yusa—the assumed name of Emilia—and the angels who monitor his actions. Amidst a violent argument between Sadao and Emi, a dimensional portal suddenly appears, carrying a mysterious apple that harbors a toddler named Alas Ramus. To everyone's bewilderment, she imprints on Emi and Sadao, marking them as her parents! After Emi reluctantly agrees to help Sadao take care of Alas Ramus, their semblance of normal life is jeopardized by the appearance of the archangel Gabriel, who comes bearing bad news. He claims that he must take both Alas Ramus and Emi's sacred sword with him—lest the world be destroyed. Unable to accept Gabriel's grim prophecies, the hero and the former Demon Lord need to put their differences aside and unite to protect what they hold dearest.

Second season of Hataraku Oniisan!. Calico Tapio Chatorazawa has more energy than anyone, and Russian Blue Kuehiko Roshihara is a bit of a sourpuss. These two classmates will do all kinds of different jobs to learn how fun and hard it is to work! (Source: Crunchyroll, edited)