Based on the horror novel by Fujio (A) Fujiko.

Edward Elric, a young, brilliant alchemist, has lost much in his twelve-year life: when he and his brother Alphonse try to resurrect their dead mother through the forbidden act of human transmutation, Edward loses his brother as well as two of his limbs. With his supreme alchemy skills, Edward binds Alphonse's soul to a large suit of armor. A year later, Edward, now promoted to the fullmetal alchemist of the state, embarks on a journey with his younger brother to obtain the Philosopher's Stone. The fabled mythical object is rumored to be capable of amplifying an alchemist's abilities by leaps and bounds, thus allowing them to override the fundamental law of alchemy: to gain something, an alchemist must sacrifice something of equal value. Edward hopes to draw into the military's resources to find the fabled stone and restore his and Alphonse's bodies to normal. However, the Elric brothers soon discover that there is more to the legendary stone than meets the eye, as they are led to the epicenter of a far darker battle than they could have ever imagined.

Sergeant Sousuke Sagara returns to Jindai High School to protect the precious war asset, Kaname Chidori, from any threat. However, his lack of social skills and real-life experience result in comical yet dangerous situations, endangering the peaceful school life Kaname longs for. As Sousuke continues to bring a wide range of weapons to school as a means to solve threats—real or fake—Kaname struggles to fulfill her duty as the student council vice president all while keeping him in check. To ensure a successful mission, Sousuke is occasionally forced to use the costume of a famous amusement park mascot called Bonta-kun. With his technical expertise, he eventually transforms the exuberant uniform into a cutting-edge exoskeleton that has only one dysfunction: the voice translator can only produce the sound mofu. Full Metal Panic? Fumoffu depicts the adventures of Kaname and Sousuke as they try to live their normal school lives despite the chaos they inadvertently cause.

Shikidouji, the illustrator of Shoji Gatoh's Full Metal Panic! light novel series, revealed that production has been green-lit on a director's cut version of the first Full Metal Panic!! television anime series from 2002. The director's cut will consist of three films. The announcement does not state if the film trilogy will add new footage. (Source: ANN)