Angelise Ikaruga Misurugi is the first princess of the noble Misurugi Empire. The kingdom has seen great power and prosperity due to the advancement of the revolutionary technology known as Mana, an abstract bending of light that has reduced the world's problems of war and pollution to a timeless peace. However, not all are blessed with the ability to wield Mana. Those who cannot are labeled Norma, outcasts of society who are considered a threat to civilization and live under constant persecution, and Angelise herself is one of many who want the Norma exterminated. But as Angelise's sixteenth birthday commences, it is discovered in a shocking revelation that she is actually a Norma. Chaos ensues, the public is outraged, and the once adored princess is exiled to Arzenal: a remote military base where Normas are forced into conscription. Now, the former royal must adapt to a harsh and vastly different lifestyle; piloting mechanical robots known as Paramail to fend off large, devastating beasts referred to as DRAGONs. However, a sinister truth about these savage creatures threatens to change everything.

In a world where half-human, half-animal chimeras live and work alongside normal people, there are sure to be a few bad apples in the bunch. Unfortunately, half-human criminals means non-human clues that often leave the police stumped. That's where lone wolf detectives like Hiroshi Inaba come in. He's literally part wolf and has the amazing ability to extract critical information just by examining or tasting a sample of someone's hair! Of course, that ability has also resulted in Inaba having a little bit of a hair fetish, but that doesn't seem to be a problem for his two assistants. (Well, at least the cross-dressing one isn't complaining much.) And it's nothing compared to the strange tastes of Inaba's nemesis, the omnivorous (and half goat) crime boss Don Valentino, who has an appetite for green legal tender instead of tender young greens! Inaba's sworn to cut Valentino out of the criminal flock before the Don can wolf down more ill-gotten dough, but he's going to have to chew his way through a lot of evidence to get his goat. Can sheer dogged detective work put the baaaaad guys behind bars? (Source: Sentai Filmworks)

Dreams are doomed to die in Night City, a futuristic Californian metropolis. As a teenager living in the city's slums, David Martinez is trying to fulfill his mother's lifelong wish for him to reach the top of Arasaka, the world's leading security corporation. To this end, he attends the prestigious Arasaka Academy while his mother works tirelessly to keep their family afloat. When an incident with a street gang leaves David's life in tatters, he stumbles upon Sandevistan cyberware—a prosthetic that grants its wearer superhuman speed. Fueled by rage, David implants the device in his back, using it to exact revenge on one of his tormentors. This gets him expelled from the academy, shattering his hopes of ever making his mother proud. After witnessing David's newfound abilities, the beautiful data thief Lucyna Lucy Kushinada offers to team up with him, handing him a ticket to salvation. However, associating with Lucy introduces David to the world of Edgerunners—cyborg criminals who will break any law for money. Edgerunners often lose their lives, if the cyberware does not break their minds first; but in his fight for survival inside a corrupt system, David is ready to risk it all.

The story will depict Joe Shimamura and the other cyborgs' struggle with the Bresudo, a group of people who possess superhuman powers and intellect, and have manipulated human history since ancient times. Their goals are unknown, and they cast a dark shadow over the world. Though few people believe in the Bresdo's existence, one American journalist named Lucie Davenport heads to Texas to contact a certain family, and she meets the cyborgs. The cyborgs themselves have been freed from their duty of protecting humanity ever since the establishment of the UN Guardian troops, and they now live quiet lives of peace.