Takehito Kumagami's clairvoyance leads his group of friends to another child with supernatural powers: Iori Sekiguchi, a mind reader. However, as they try to approach her, they realize her power makes her nearly impossible to pin down. Having been chosen by the club to handle this case, Nao Tomori and Yuu Otosaka must find a way to get around the child's unique ability before it is too late.

If not for his ability to take over people's mind and body, Yuu Otosaka would be an ordinary high school student. Though it only lasts for five seconds at a time, Yuu's mysterious power allowed him to cheat his way to the top of his class and enter a prestigious high school, where he continues his dishonest acts. His shenanigans are eventually stopped by Nao Tomori—the headstrong student council president from Hoshinoumi Academy—who sees through his deceit. Through coercion, Nao convinces Yuu to transfer to Hoshinoumi and join the student council. Hoshinoumi Academy is secretly an institution created for adolescents who possess supernatural abilities—with the student council serving as a means of locating those who abuse their powers. With Yuu begrudgingly assisting in council affairs, the group sets out to find and protect new ability users from harm. However, as they further investigate the abilities, their findings entangle them in far more complicated matters than they could ever imagine.

In 3015, the year of Huanli, two countries, Donatia and Kouran, are embroiled in a war of supremacy that is tearing the world around them apart. The small island Nil Kamui has suffered exceptionally from the war, with lands conquered in the name of each kingdom and stolen away from the people. To make matters worse, their deity, the Red Dragon, has gone mad, rampaging about Nil Kamui burning villages and killing people indiscriminately. Ibuki, a descendant of Nil Kamui's royal family, resides at an orphanage and refuses to take on the role of king. Abhorring conflict, Ibuki desires a peaceful resolution, however the chaotic world will not allow for such pacifism when it is being torn asunder by war. Despite his reluctance, Ibuki is drawn deep into this conflict. Can he rise to the occasion and save his country?

A series of gruesome murders dubbed New Generation Madness once induced mass hysteria in Shibuya. At its peak during a frenzied riot, a sudden earthquake reduced the district into nothing but rubble, while leaving surrounding wards strangely intact. Six years later, in a newly rebuilt Shibuya, mysterious deaths begin to crop up again. It is not long before third-year student Takuru Miyashiro realizes a connection: the dates of the recent murders match those of the New Generation Madness incidents. He, along with several members of his school's newspaper club, decide to delve deeper into the mystery, only to find themselves stranded in the middle of a new crime scene themselves...