In the current era, a small percentage of people called Special Abilities have skills and powers normal humans do not possess. An autonomous organization, the Deviant Control Office, keeps these Special Abilities in check. Though some wish to maintain this order and peace, some wish to take advantage of their abilities and obtain more power in this world.

Litchi DE Hikari Club takes place in an alternate reality where the Hikari Club does not fall into disarray after the completion of Litchi, the intelligent humanlike robot the club invented to kidnap girls. The cult-like Hikari Club has had its ups and downs. Led by the enigmatic, beauty-obsessed Hiroyuki Zera Tsunekawa, the club has finally succeeded in using their fruit-powered robot, Litchi, to kidnap the beautiful Kanon. After accomplishing their goals, the Hikari Club has little to do other than delight in their newfound lives. From selling the technology that allows Litchi to run on lychee fruit, to modifying the robot to perform different tasks, there's no telling what antics the Hikari Club will get up to next!

The protagonist of the story, Konoha Inoue, is a seemingly normal senior high 2nd year student. His high school life, other than a hinted incident 2 years ago, can be summed up as normal- if one can dismiss the secret fact that he used to be a female bestselling romance author. Due to that incident, however, he has now vowed never to write again. This continued on until he was forced to join the literary club by the literary club president, the 3rd year female student Amano Tooko, a beautiful girl who has a taste for eating literary works. Now he has been tasked with writing her snack every day after school. (Source: To Say Nothing of the Dog)

Following the Little Busters after they lost their first baseball game, the team decides to have a pancake party. It has been almost one semester since the return of Kyousuke Natsume. As usual, Riki Naoe continues to help the Little Busters' members—both old and new—with confronting their inner struggles. However, strange happenings begin to occur, leading Rin Natsume and Riki closer to unraveling the truth behind the secret of this world. Little do Rin and Rikki know, their discovery will end up changing the peaceful everyday lives created by the Little Busters once and for all. Little Busters!: Refrain brings a conclusion to the colorful stories of its ensemble cast—forged with the weight of emotions and strengthened with the bond of friendship—as they come to terms with their regrets and weaknesses.