Earth's once green hills and rich blue oceans have been converted into a desolate wasteland by the relentless onslaught of planet bombs from the expansionist Gamilas Empire. By the year 2199, humankind has retreated to the depths of underground cities to escape the radiation. However, all hope is not lost, as the distant planet Iscandar offers Earth its final salvation: the Cosmo Reverse System, capable of restoring Earth's irradiated surface. In a desperate bid to retrieve this technology from Iscandar, the Earth Defense Force pours its remaining resources into the Yamato—an innovative, state-of-the-art battleship equipped with an infinite energy Wave Motion Engine. From young talent such as Tactical Officer Susumu Kodai to accomplished veterans like Captain Juuzou Okita, the Yamato's crew consists of many individuals, all varying in their experience on the battlefield. But despite their differences, one goal unifies them all: to complete their perilous 168,000 light-year voyage to Iscandar and save humanity from imminent doom.

The year is 2203, not long after the Bolar Federation was defeated by Desslok's Galman-Gamilon Empire. A subspace dimensional dislocation has caused a distant Red Galaxy to be relocated in a collision course with the Milky Way. Stars and planets collide, making a wreck of the Galman-Gamilon homeworld. The Star Force is dispatched to investigate. They reach Galmania to find Desslok's palace in ruins. As they pay their respects, tossing white roses down to the surface of the planet, a huge red planet crashes into Galmania, forcing to StarForce to escape with an immediate and uncalculated warp. (Source: AniDB)

A crisis is approaching Earth with the expansion of a moving black hole, in the year 2220. A plan is devised to move over 300-million people from Earth. When the latest transportation fleet is attacked, Space Battleship Yamato comes to its defense, the ship is now commanded by Susumu Kodai, also aboard is daughter Miyuki, child of Susumu and Yuki. (Source: FUNimation)

Three years since the return of the legendary Space Battleship Yamato, Earth has begun rebuilding itself and has made peace with the Gamilans. However, this recovery comes at the cost of utilizing the forbidden Wave Motion technology. Meanwhile, the notorious former crew members of the Yamato, who have each gone their separate ways, receive a psychic message from the mysterious Goddess Teresa. She urges them to return to their beloved ship and travel to the distant planet Terezart. They are promised a revolutionary power to combat the unprecedented threat of the relentless Gatlantis Empire, who are approaching Earth with all but innocent intentions. Unable to resist her plea, the crew reassembles and sets sail on another perilous intergalactic voyage, one that will test their sheer courage and versatility in the face of an even greater foe.