In the year 2041, World War III has wiped out two-thirds of the human population, and in the newfound structure, the belief in any god or beyond-human entity is considered a preposterous notion. In order to prevent citizens from bearing possibly incriminating thoughts, the government has assembled a Special Weapon Enforcement division to capture and rehabilitate such believers. The Kirihara brothers, Naoya and Naoto—who were hidden away from society by their captors for years to conceal their psychic abilities—were promised freedom once the world was ready to face their existence. Now, wandering in the appalling new societal climate where psychics are not welcome, the brothers find themselves on the run from the Enforcement's devoted operatives, Yuuya and Takuya Kuroki.

Following a 15-year long seclusion in a research facility, brothers Naoto and Naoya Kirihara finally escape after the psychic barrier separating them from the outside world collapses. Abandoned by their parents, who feared their supernatural powers, the siblings now strive for a normal life. However, the two are soon forced to use their talents to save lives as the minus energy begins to engulf the world and crimes involving psychic abilities gradually multiply. Learning to control their capabilities and using them for the sake of others will prove challenging, for Naoya is traumatized by his psychic abilities that allow him to read people's minds; while Naoto has hurt many close ones due to his unstable psychokinetic powers. With the help of the mysterious Shouko Futami, who can see into the future, the Kirihara brothers must find a way to foil the plans of an organization that seems to be linked to the harmful events related to gifted individuals.

On Filiel's 15th birthday, she received her mother's necklace as a memento from her obstinate astronomer father. Her common and tedious life was turned into a life of conspiracies. With her new life, many adventures await. (Source: ANN)

On a sunny afternoon in her Paris apartment, assassin-for-hire Mireille Bouquet receives a strange email from Kirika Yuumura, a young student from Japan, inviting her to make a pilgrimage to the past together. Initially thinking the email is nonsense, she changes her mind when it begins playing a song that she recognizes from her youth. Upon first meeting each other in person, the two are suddenly ambushed by gun-wielding men. While Mireille is capable of fending off the assault, she discovers that Kirika is quite adept in combat situations after she takes out several gunmen on her own. Despite her proficiency at killing, Kirika laments her inability to feel remorse for her victims. In addition, Kirika apparently has no memory of how she came to acquire the skills she possesses or even of her real identity. Sensing shared history between them, Mireille agrees to team up with Kirika, and together, they embark on a journey to uncover the mysteries of their pasts. Operating under the codename Noir, the duo's fragile alliance is tested as they begin accepting jobs, each one bringing them closer to the truth of who they really are.