Third season of Youkoso Jitsuryoku Shijou Shugi no Kyoushitsu e.

There are rumors that one of Kamome Academy's Seven Mysteries, Hanako-kun, has gained an assistant: first-year high school student Nene Yashiro. Together, Hanako and Yashiro investigate the school's many mysteries, keeping the balance between humans and the supernatural. But in their free time, the two can often be found goofing off, engaging in various antics involving Yashiro's schoolmates and the lurking spectral entities that normal people cannot see.

Through their combined effort, the members of PathTLIVE have made it to the Virtual Grid Awards at ADEN Academy. Miracle, Chris, Quan, Riz, and Noelle—along with several other top virtual artists—will compete in the main event of the ceremony: a Unit Battle, where participants enter as a team to compete for a spot in the main event's concert. As the competition heats up, PathTLIVE reviews their competitors who have made it to the main event and evaluates if they have what it takes to win. But when the girls begin to lose confidence, they look inward to see how they can improve themselves to prepare for the Unit Battle. Through collaborations with other top performers, each girl explores new facets of what it means to be a virtual artist.

Following a series of attacks that have left teachers and students alike sapped of their magic, headmistress Liza Quillyn decides to seal off the College, rendering it impossible to enter or leave the premises. As a result, Philomela Sargant is unable to comply with her grandmother Lizbeth's order to withdraw from the school. Trapped inside the College, Chise Hatori and her classmates begin to adjust to their novel and stressful circumstances. But as time goes on, Philomela's condition only gets worse—both mentally and physically. Meanwhile, details about the tragic past of Chise's roommate, Lucy Webster, continue to resurface. As Chise grapples with worries about her friends and with her evolving self, the identity of the mysterious magic-draining culprit plaguing the College may finally come to light.