Despite the destruction of the mechanization home world Andromeda, the machine empire is still swept across the galaxy and Earth has become a battleground. Having returned from his journey aboard the train Galaxy Express 999, Tetsurou Hoshino joins the resistance and fights alongside others who have retained their humanity. When the 999 returns to Earth, Tetsurou receives an enigmatic recorded message from his former traveling companion Maetel, telling him to board the train once more. Fighting his way to Megalopolis station, he makes it onto the train just as it departs. This time, however, Tetsurou is met with several mysteries: Maetel is nowhere to be seen, an ominous Ghost Train has appeared, and the ultimate destination of the 999 is unknown. Amid all this, Tetsurou finds himself confronted by the mysterious black knight Faust and soon discovers the machine empire's darkest secret.

Sometime in the near future, in an age in which we have established contact and communications with planets outside our galaxy, Scan2Go has become a huge phenomenon throughout all of outer space. Giant races are held at every locality, with each racer gunning for the title of the universe's number one racer! The main character in the series, Kazuya, possesses the power of the eagle, performed well with his blazing, innate power commanding his falconine beast spirit. He competes in a tournament, the Pro-Racer Exhibition Race., but was no match for the other teams that had won their way through the competitive Space Preliminaries. Realizing the difficult obstacles that lie before them, Kazuya and his friends leave the small Earth behind and set off on a universe-wide quest to hone their skills as warriors!

The Blue World, which symbolizes reason, is under constant attack by the creatures called the Nightfly O'Note originating from the Red World, symbolizing instinct. Akira Asagi, the 17-year-old protagonist who is a researcher at Blue World, is nominated to lead the war at Ryuukyuu LAG, a proud defense facility on the islands of Ishigaki and Iriomote. She meets the sixth combat unit IS, which was formed four years after a fierce battle that annihilated the fifth unit. Akari must lead these six riders, also called the Scared Rider Xechs, to fight against the other world while at the same time deepening the relationship among them. (Source: MAL News)

In the year 2020, a nation faces the pervasive threat of the Others—mysterious monsters who fall from the sky and feed on human brains. At the same time, psionics, a hormone that gives certain people extrasensory abilities that are effective against the Others, is discovered in the human body. Subsequently, the nation's founder establishes the Other Suppression Force (OSF) to combat these monsters and save humanity. Commonly referred to as the Scarlet Guardians, young individuals with psionics undergo intensive training to join this group. One day, the nation prepares an induction ceremony for the exceptional recruits who completed the grueling training to become Scarlet Guardians. Among these young elites is Yuito Sumeragi, the determined son of the nation's founder; at the age of five, he was rescued by a woman in the OSF. To repay this debt, he joins the organization, eager to put his training to good use. As he meets his new comrades, he faces a big problem—the woman who saved him years ago closely resembles one of his teammates. However, this should be the least of his worries—unbeknownst to him, a conspiracy is brewing, one with the capability to shake the entire country.