Following the revelations of the archangel Gabriel, Ente Isla hero Emilia Justina—who lives on Earth under the alias Emi Yusa—starts doubting the validity of her mission to slay the Demon Lord Satan, now reduced to a modest employee of MgRonald's as Sadao Maou. At the same time, Sadao's high school-aged coworker Chiho Sasaki pursues a new dream with hopes to protect not only herself but also her friends. Secretly training with Emi and Suzuno Kamazuki to develop telepathic powers, Chiho's training is cut short when a group of demons abducts her. As angel and demon attacks threaten the fragile peace between the two worlds, Sadao and Emi need to put their troubled past behind them if they want to have a chance to find their new purpose in life.

Onmyouji tells the story of renowned onmyouji Abe no Seimei, who meets and befriends the straightforward court noble Minamoto no Hiromasa. Together, they deal with strange cases in the Heian capital surrounding demons and curses.

After succeeding in their winter conflict against Taiju Shiba and his Black Dragons, the Tokyo Manji Gang absorbs their group's remaining members. Due to his heroic courage and indomitable spirit, Takemichi Hanagaki should have accomplished his goal of defeating the tragic fate awaiting his girlfriend, Hinata Tachibana. In reality, Takemichi's troubles are far from over. Although Takemichi's actions have exposed Tetta Kisaki's treachery, the conniving schemer has found power elsewhere: Tenjiku, a dangerous gang led by the enigmatic Izana Kurokawa. Izana sets his sights on Manjirou Mikey Sano, pursuing a vicious interest in the Tokyo Manji Gang's aloof leader. In the future, Takemichi discovers that the machinations of Izana and Kisaki led to Mikey's moral ruin—a downfall that directly results in Hinata's death. Unfortunately, a terrible loss robs Takemichi of his time-leaping ability, stranding him in the past with one final chance to rescue everyone he loves.

Since childhood, 15-year-old Umika Konohoshi has been fascinated by aliens, hoping to one day voyage to outer space and befriend them. Unfortunately, this fixation has caused her peers to label her as odd, intensifying her struggle with severe social anxiety. Nevertheless, Umika's passion for the extraterrestrial persists, and she deeply believes that her true purpose is outside the confines of Earth. On her first day of high school, Umika's wish of meeting an alien seems to have finally come true when she encounters Yuu Akeuchi—a classmate who claims to have crash-landed on Earth with no recollections of her past. Umika tries to seize this opportunity to make friends with Yuu, but her lack of confidence hinders her. Sensing Umika's distress, Yuu suddenly uses a strange power to delve deep into her mind, thus sparking a friendship that may just help Umika reach her dreams.