The God of High School tournament has begun, seeking out the greatest fighter among Korean high school students! All martial arts styles, weapons, means, and methods of attaining victory are permitted. The prize? One wish for anything desired by the winner. Taekwondo expert Jin Mo-Ri is invited to participate in the competition. There he befriends karate specialist Han Dae-Wi and swordswoman Yu Mi-Ra, who both have entered for their own personal reasons. Mo-Ri knows that no opponent will be the same and that the matches will be the most ruthless he has ever fought in his life. But instead of being worried, this prospect excites him beyond belief. A secret lies beneath the facade of a transparent test of combat prowess the tournament claims to be—one that has Korean political candidate Park Mu-Jin watching every fight with expectant, hungry eyes. Mo-Ri, Dae-Wi, and Mi-Ra are about to discover what it really means to become the God of High School.

Two years have passed since the end of the Fourth Great Ninja War. Konohagakure has remained in a state of peace and harmony—until Sixth Hokage Kakashi Hatake notices the moon is dangerously approaching the Earth, posing the threat of planetary ruin. Amidst the grave ordeal, Konoha is invaded by a new evil, Toneri Oosutuski, who suddenly abducts Hinata Hyuuga's little sister Hanabi. Kakashi dispatches a skilled ninja team comprised of Naruto Uzumaki, Sakura Haruno, Shikamaru Nara, Sai, and Hinata in an effort to rescue Hanabi from the diabolical clutches of Toneri. However, during their mission, the team faces several obstacles that challenge them, foiling their efforts. With her abduction, the relationships the team share with one another are tested, and with the world reaching the brink of destruction, they must race against time to ensure the safety of their planet. Meanwhile, as the battle ensues, Naruto is driven to fight for something greater than he has ever imagined—love.

At the request of his father, tennis prodigy Ryouma Echizen has returned from America and is ready to take the Japanese tennis scene by storm. Aiming to become the best tennis player in the country, he enrolls in Seishun Academy—home to one of the best middle school tennis teams in Japan. After Ryouma catches the captain's eye, he finds himself playing for a spot on the starting lineup in the intra-school ranking matches despite only being a freshman. Due to his age, the rest of the Seishun Boys' Tennis Team are initially reluctant to accept him, but his skill and determination convinces them to let him in. Armed with their new super rookie, Seishun sets out to claim a spot in the National Tournament, hoping to take the coveted title for themselves. In order to do so, the team must qualify by playing through the Tokyo Prefectural and Kanto Regionals. Yet, the road ahead of them is shared by a plethora of strong schools, each playing tennis in unique ways for their own reasons. Ryouma and his teammates must learn to cooperate if they want to become the champions they aspire to be.

In Stern Bild City, those with special abilities are called NEXT, and can use their powers for good or bad. A unique organized group of NEXT appear regularly on Hero TV, where they chase down evildoers to bring limelight to their sponsors and earn Hero Points in the hopes of becoming the next King of Heroes. Kotetsu T. Kaburagi, known as Wild Tiger, is a veteran hero whose performance has been dwindling as of late, partially due to his inability to cooperate with other heroes. After a disappointing season in which most of the other heroes far outperformed Tiger, he is paired up with a brand new hero who identifies himself by his real name—Barnaby Brooks Jr. Barnaby, nicknamed Bunny by his frivolous new partner, quickly makes it clear that the two could not be more different. Though they mix as well as oil and water, Tiger and Bunny must learn to work together, both for the sake of their careers and to face the looming threats within Stern Bild.