Fuutarou Uesugi is an ace high school student, but leads an otherwise tough life. His standoffish personality and reclusive nature have left him friendless, and his father is debt-ridden, forcing his family to scrape by. One day during his lunch break, Uesugi argues with a female transfer student who has claimed his seat, leading both of them to dislike each other. That same day, he is presented with a golden opportunity to clear his family's debt: a private tutoring gig for a wealthy family's daughter, with a wage of five times the market price. He accepts the proposal, but is horrified to discover that the client, Itsuki Nakano, is the girl he confronted earlier! After unsuccessfully trying to get back on Itsuki's good side, Uesugi finds out that his problems don't end there: Itsuki is actually a quintuplet, so in addition to her, he must also tutor her sisters—Miku, Yotsuba, Nino, and Ichika—who, despite the very real threat of flunking, want nothing to do with a tutor. However, his family's livelihood is on the line so Uesugi pushes on, adamant in his resolve to rid the sisters of their detest for studying and successfully lead them to graduation.

The continuation of Yurumates 3D right after the first season.

Saya Otonashi is a seemingly ordinary girl living a mundane life with her adoptive family in Okinawa City. In fact, her only peculiarities are suffering from anemia and being unable to remember any of her life beyond the previous year. However, Saya's forgotten past quickly comes back to haunt her—one night, she is attacked at school by a creature that feeds on human blood. Just when all hope seems lost, a mysterious man named Haji appears and fends off the creature temporarily. But when her rescuer forces her to drink his blood, Saya suddenly enters a trance and slays the monster with ease, using her own blood as a catalyst. Saya then learns of an organization named Red Shield, founded for the sole purpose of defeating the hellish beasts. Now Saya and Haji must work together with Red Shield to fight these fearsome monsters and unlock the secrets to the girl's past.

The year is 1931. The city is Shanghai. Ten years before America will enter World War II, the hydra's teeth planted by the first great global conflict are beginning to germinate. Hatching like spiders, they weave the complex web of plots and conspiracies destined to inevitably draw entire nations to the brink of destruction. Caught in the heart of these webs, desperately seeking to separate lies from truth, is Sakurai Kikan, an ultra-secret intelligence agency staffed by extraordinarily talented individuals with abilities far beyond those of normal humans. Their duty: to stop the darkest plots and eliminate the greatest threats. But in a city built on intrigue, can even a team of clairvoyants, telepaths and espers stand against the ultimate forces of destiny? (Source: Sentai Filmworks)