He's small, fluffy, and absolutely adorable: Hamtarou is one perfect little hamster! After moving to a new house with his owner, 5th grader Hiroko Haruna, Hamtarou discovers other hamsters and quickly makes friends. The group of hamster explorers call themselves the Ham-Hams, and there's nowhere they won't go. The Ham-Hams go on crazy adventures all around the city while their owners are away, visiting everything from plays to magical lands of candy. Meanwhile, the humans face their own dramas.. Hamtarou meets a huge cast of different personalities, gets himself into—and out of—some pretty tight spots, and even helps Hiroko and her friends out more than once. Through it all, he never stops being unbearably cute. It's Hamtarou time!

Living an abnormal existence in Ogikubo, an intergalactic melting pot of humans and aliens as well as the only Space Immigration Zone on Earth, Luluco is a bubbly middle school girl who just wants to be normal. One morning, however, her father, who works at the Space Patrol, eats a volatile sleep capsule by mistake and is frozen solid! To make matters worse, Luluco accidentally breaks him, so she hurries off to his office for help. There, the chief of the Space Patrol, Over Justice, hires Luluco as a space temp worker for undercover investigations, so that the institution may crack down on crime within her school. Made to don the Space Patrol suit and sent on her way to mete out justice, Luluco attempts to maintain the image of a normal girl who does not stand out in any way. But she soon discovers that with the automatic systems and inherently zealous judiciousness of the Space Patrol suit, continuing to be normal will be more difficult than she thought.

Shun Hashimoto is an openly gay aspiring novelist living in Okinawa who was abandoned by his parents after coming out to them. Mio Chibana is a reserved, orphaned high school student, often found spending his time by the sea. One day, the two meet on the beach, and Shun is instantly captivated by Mio. The days fly by as they slowly begin to grow closer until Mio suddenly announces that he has to leave for the mainland. Three years pass before a 20-year-old Mio returns to Okinawa to confess his love to Shun. However, in those three years, Shun's life has changed. Will he be able to accept Mio's feelings and make such a commitment?

An injured man is found in the woods by a girl named Eruruu, and everything about him is mysterious. Without knowledge of his past nor even his own name, he is welcomed to Eruruu's home and is given the name Hakuoro by her grandmother, and younger sister, Aruruu. While the inhabitants of the village have large ears and tails, Hakuoro's defining physical trait is quite different as he has neither ears nor tail, but only a mask that he cannot remove. Soon after he becomes a part of the villagers' lives, a revolution against the tyrannical emperor of the land begins, and the conflict finds its way to his new home. Hakuoro must do whatever he can to save the people and the village that he has come to love, all while uncovering the mysteries that shroud his past.