In a research facility hidden away on a remote island, genius programmer Shiki Magata has lived as a recluse for years. She rarely sees guests, but associate professor Souhei Saikawa and university student Moe Nishinosono still seek her out. However, their meeting is cut short when they are caught up in a locked-room murder mystery. Everything is not as it seems, and many secrets are hidden. Within an isolated facility, a seemingly impossible and gruesome crime takes place, and Saikawa and Moe must unravel the truth behind the murder and Magata's shrouded past.

Princess Anisphia Anis Wynn Palletia has always dreamed of flying through the sky, even though the people of her kingdom consider it a silly ambition. Also at odds with her goal is the fact that Anis is incapable of using magic despite her noble status. Refusing to give up so easily, she renounces her right to the throne, and focuses on developing magicology by combining various resources with knowledge from her previous life on Earth. Due to Anis' nature, responsibility for the kingdom's future is passed onto her younger brother, Algard. Pushed into a political marriage with Euphyllia Magenta, a girl he hardly knows, Algard rebels by spending more time with a commoner girl than his fiancée. After Euphyllia tries to intervene, Algard publicly calls off their marriage and denounces his ex-fiancée as a bully. After crashing into the banquet where Algard makes the announcement, Anis rescues Euphyllia on the flying broom she is testing. She decides to make Euphyllia her assistant, which the other girl reluctantly agrees to. Although their partnership appears random at first, Anis has an ulterior motive for wanting Euphyllia's company.

Famous racehorses that have left behind worthy legacies, unique as they can be, are reincarnated as horse girls in a parallel world. In this life, they start their journey anew as they continue to race and perhaps relive the success they once lived through. Aspiring to become the best racehorse in Japan, a horse girl named Special Week moves to Tokyo to enroll in the Tracen Academy—an institution that nurtures horse girls like her to become better racers. There, Special Week witnesses the sophisticated running style of Silence Suzuka and is inspired to become a racer like her. Shortly after, Special Week finds herself recruited into Silence Suzuka's team, Spica. From there, she begins her path to the top—one lap at a time.