In a dystopian future where Japan's political organization has crumbled after the Great Tokyo War, Japan is broken up into 10 independent nations, with each nation controlled by a gang led by a Best, a human-proclaimed prophet with destructive superpowers. Nozomi Moritomo is a Rest—a normal girl that has just started out as a rookie in the local gang. She wants to help the Best Masami Utoku, her childhood friend and role model, in the ongoing territorial dispute. When Masami becomes severely injured and unable to fight, Nozomi decides to go on a mission to complete the requests sent to Masami from all over Japan. Along the way, she meets Yukina Kosaka, a shy girl with no sense of direction; Ai Hibiki, an upbeat girl who loves eating; and Chiaya Misono, a quiet and mysterious girl that wears a gas mask. Together, the four girls travel all over the country on their motorcycles while getting involved in territorial wars, disagreements, and even suspicious conspiracies.

In Stern Bild City, those with special abilities are called NEXT, and can use their powers for good or bad. A unique organized group of NEXT appear regularly on Hero TV, where they chase down evildoers to bring limelight to their sponsors and earn Hero Points in the hopes of becoming the next King of Heroes. Kotetsu T. Kaburagi, known as Wild Tiger, is a veteran hero whose performance has been dwindling as of late, partially due to his inability to cooperate with other heroes. After a disappointing season in which most of the other heroes far outperformed Tiger, he is paired up with a brand new hero who identifies himself by his real name—Barnaby Brooks Jr. Barnaby, nicknamed Bunny by his frivolous new partner, quickly makes it clear that the two could not be more different. Though they mix as well as oil and water, Tiger and Bunny must learn to work together, both for the sake of their careers and to face the looming threats within Stern Bild.

Since ancient times, shrine maidens who wield swords have been exorcising aratama, strange existences that threaten the human world. These young women who wear school uniforms and a sword are called Toji, and they serve as an official unit within the police force as a special religious service police squad. The government authorizes the Toji to wear swords and serve as government officials, and the government has set up five schools throughout the country for the girls to attend. In the spring, the five schools send their best Toji to compete in a tournament. As the tournament comes closer, all of the representatives rigorously train themselves in order to get stronger and improve their skills. (Source: ANN)

Throughout history, an elite group of shrine maidens known as Toji have saved the world from Aratama, strange and malevolent beings bent on destroying humanity. In modern times, these warriors have been assigned to a special police squad to exterminate Aratama. The government has also set up five elite schools across the country to provide young girls the necessary sword fighting skills to eradicate these monsters and eventually join their fellow Toji in protecting the world. A student of one of those five schools, Kanami Etou is chosen to represent Minoseki Academy in a sword fighting tournament, where she meets the mysterious Hiyori Juujou. Although Kanami and Hiyori rise to the top of the tournament, their battle takes an unexpected turn, throwing the world of the Toji into chaos. Likely that the Toji are facing betrayal from within, the two are forced to flee the tournament, clashing with former comrades on the way.