At True Cross Academy, Rin Okumura unknowingly comes across the first signs that something is amiss; ordinary people have been gaining the ability to perceive the invisible creatures that roam the human realm, Assiah. While Rin sees this as an opportunity to make a new friend, his twin brother, Yukio, is more burdened than ever. Swamped with his education, exorcist duties, and teaching position, Yukio has remained silent about his awakened powers, unable to understand their scale or significance. While Rin and his friends prepare for the annual Exorcist Certification Exam, the True Cross Order has uncovered the first artificial gate to the demonic realm of Gehenna. Witnessing its size and the advanced technology that made it possible, the exorcists realize they are now dealing with the Illuminati, an extremely wealthy and powerful organization. Moreover, the inscrutable Illuminati have planted three spies in the True Cross Order—and one may be hiding among the aspiring exorcists sworn to protect mankind from the demonic threat.

Eight-year-old Pride Royal Ivy suddenly recalls her former life as a fan of the otome game Our Ray of Light. While on her way to replay it, she tragically died, reincarnating as the game's final boss and firstborn princess of Freesia. Her knowledge of the game's events leads everyone to believe she has the power of precognition. But unlike the game's original princess, this new Pride does not wish to torment those around her, such as her younger sister and adopted brother. Haunted by nightmares of her other self's atrocities, Pride resolves to protect her family and country while progressing the story. As the world around her changes, she prepares for the day she will have to die at the hands of the game's main characters. Nevertheless, before that happens, Pride will either transform her kingdom for the better or fall under the weight of her possible crimes.

Ten years ago, a volcanic eruption brought Japan's Ayaka Islands to the brink of destruction. Since then, Yukito Yanagi has lived with foster families on the mainland, but he has isolated himself from others following a disturbing incident. Due to the wishes of his late father, Makoto, Yukito is brought back to his birthplace on the day of his middle school graduation. There he meets Makoto's disciples and learns of the supernatural state of the region. Mysterious life forms known as Mitama inhabit the islands, but their potential to feed off humans' negative energy and turn into ferocious monsters called Ara-Mitama endangers the islanders' lives. Yukito discovers that, like his father, he is a Ley Master—a special individual with abilities akin to magic, tasked with pacifying the Ara-Mitama. As he learns to overcome his trauma and control his powers, Yukito decides to follow in his father's footsteps and become a first-rate Ley Master to protect the peace of Ayaka.

Following the revelations of the archangel Gabriel, Ente Isla hero Emilia Justina—who lives on Earth under the alias Emi Yusa—starts doubting the validity of her mission to slay the Demon Lord Satan, now reduced to a modest employee of MgRonald's as Sadao Maou. At the same time, Sadao's high school-aged coworker Chiho Sasaki pursues a new dream with hopes to protect not only herself but also her friends. Secretly training with Emi and Suzuno Kamazuki to develop telepathic powers, Chiho's training is cut short when a group of demons abducts her. As angel and demon attacks threaten the fragile peace between the two worlds, Sadao and Emi need to put their troubled past behind them if they want to have a chance to find their new purpose in life.