Gakusen Toshi Asterisk 2nd Season continues the story of Genestella students Ayato Amagiri and Julis-Alexia von Riessfeld, who have progressed to the next round of the Phoenix Festa after a long and strenuous battle with sisters Irene and Priscilla Urzaiz. Despite Julis and Ayato's best attempts, the fact that Ayato's powers have been sealed is no longer a secret. Now at a major disadvantage, the duo must come up with a plan if they are to have any hope of winning the Phoenix Festa. Only one thing is for sure: the troubles heading their way are only going to get more insurmountable from here on.

In the previous century, an unprecedented disaster known as the Invertia drastically reformed the world. The powers of existing nations declined significantly, paving the way for a conglomerate called the Integrated Empire Foundation to assume control. But more importantly, the Invertia led to the emergence of a new species of humans who are born with phenomenal physical capabilities—the Genestella. Its elite are hand-picked across the globe to attend the top six schools, and they duel amongst themselves in entertainment battles called Festas. Ayato Amagiri is a scholarship transfer student at the prestigious Seidoukan Academy, which has recently been suffering from declining performances. Through a series of events, he accidentally sees the popular Witch of Resplendent Flames, Julis-Alexia von Riessfeld, half-dressed! Enraged, Julis challenges him to a duel for intruding on her privacy. After said duel is voided by the student council president, Ayato reveals that he has no interest in Festas. Instead, he has enrolled in the academy to investigate the whereabouts of his missing elder sister. But when a more devious plot unravels, Ayato sets out to achieve victory, while being surrounded by some of the most talented Genestella on the planet.

Lufy, discovered floating lifeless in space, is brought on board a Solnoid cruiser and given another chance at life. Once the hardened warrior, she is shown events that shake her faith (one's own death seems to have a way of changing one's philosophy) and lessening her power as a fighter just as that power is most needed! (Source: AniDB)

The girls are saved ... by none other than Catty Nebulart herself! Now, the race is on as Catty struggles to complete her crowning achievement: a huge machine that will bring life to a lifeless world! (Source: AniDB)