Africa no Salaryman is a slapstick workplace comedy that follows the adventures of kind Lion, jaded Lizard, and perverted Toucan, as they trudge through office life while also becoming caught up in antics no regular office worker should. Of course, most of these are the fault of Toucan, whose selfish actions and lack of filter still haven't gotten him fired. It's up to Lizard and Lion to keep themselves out of trouble and hang on to their jobs at the office. But trouble is never too far away from these savannah-treading folk.

Splotched in blooms of color and bursting with ideas, a young artist paints another beautiful piece, his girlfriend supporting him all the while. Their lives are modest, but they know they will stay by each other no matter what. When one of his works sells, he experiences unprecedented renown; life couldn't be any better for a man with both love and success. However, the lust for creativity consumes him, and as his world crumbles around him, he is left scrambling to pick up the pieces of what remains.