The Royal Diana Academy is a prestigious school that accepts individuals with adept magical abilities. Upon graduation, these students find themselves at the top of their field or employed by the royal family. Spica Virgo dreams of studying at the academy, aiming to be a top-rate sorceress like her idol Claude Sirius. Claude is a world-renowned sorcerer who became the institution's youngest instructor, but mysteriously disappeared soon after. Lacking the experience and connections required for admission, Spica finds herself unable to make meaningful progress with her training. One day, however, she meets a talking black cat with magical abilities. Hoping to change the situation for the better, she begs the animal to take her as his apprentice and teach her the magic she needs to attend the academy. The cat accepts the deal on one condition—she must find a way to reverse his feline curse. Despite the arduous challenges ahead of her, Spica is determined to prove herself as a student worthy of the cat's mentorship.

In 2038, Yuuma Sawatari is an elementary school kid who loves everything about space and astronomy. He was initially excited when his parents bought a robot called Nanako, but he was disappointed when he learned that she was basically just a boring housekeeping robot. However, when he does finally try to talk to her about space, something strange happens. Her system crashes and is taken over by what claims to be a marooned alien ship! The alien ship wants Yuuma's help to get back to space! (Source: MangaHelpers)

Two and a half years after the dark day of the Lost JuLai, Meryl Stryfe roams in the desert wilderness of Noman's Land alongside her younger assistant, Milly Thompson. She still pursues Vash the Stampede, the culprit behind the cataclysmic events that took the lives of 90 percent of the JuLai city population. Vash, also referred to as the Humanoid Typhoon, is now sought after for 60 billion double dollars—the largest bounty in the history of the planet. In a backwater town of Noman's Land, an apathetic Vash has been rescued and cared for by Hoppered the Gauntlet, a man who covers his mutilated body with armor. But Hoppered's secluded life is abruptly interrupted by the arrival of young Jessica seeking help for her endangered home.

Following the massive operation that led to the confinement of recent recruit Kafka Hibino, otherwise known as Kaijuu No. 8, the Defense Force has been puzzled by how to deal with him. Kafka is the first kaijuu to side with humans, and after careful consideration, he is eventually transferred to the Defense Force's First Division in the hope of adding his power to the strongest division, capable of handling any threat. However, some people are still doubtful about Kafka, and he must prove his worth in the next mission. Kafka and the First Division are soon dispatched when a massive horde of ant-like kaijuu begins wreaking havoc. Thanks to the combined strength of Kafka's friend Kikoru Shinomiya and their captain, Gen Narumi, the mission seems to progress as it should. However, when Kafka fails to transform into his kaijuu form, the dreadful Kaijuu No. 9 joins the battle with only one goal—to eliminate him and steal his power. Although the situation is looking grim, Kafka must overcome his most difficult trial yet with the others if he wants to keep pursuing his dream: fighting side by side with his childhood friend and Third Division captain, Mina Ashiro.