The Yuzuki family, which consists of four brothers, lost their parents two years ago. Hayato, the eldest son, is a hard worker and the pillar of the family. Mikoto, the second son, is calm and collected, but he has a soft spot for his younger brother Minato, whom he adores and thinks is cute. Minato, the third son, is energetic and adores his brothers, but he is clumsy and awkward. Gakuto, the fourth son, is a studious and mature first-grader who is often referred to as a wise man. The manga depicts the four brothers' daily lives as they navigate their family, school, and community. (Source: MAL News)

In their last year of middle school, the five band members of CRYCHIC went their separate ways after an unpleasant disbandment. Each wrestling with their own regrets, the girls enrolled in different high schools, hoping never to hear from one another again. Meanwhile, Anon Chihaya transfers to Haneoka Girls' Academy in the middle of the school year. As most students play in a band as a hobby, Anon desires to fit in and spends her first days trying to recruit members for her own band, envisioning herself as the group's vocalist. She befriends Tomori Takamatsu, a shy girl who seems interested but hesitant about joining. As it turns out, Tomori used to be part of CRYCHIC, an experience that has scarred her deeply. Through Tomori, Anon meets Taki Shiina and Soyo Nagasaki, both former members of the same band. Although Taki detests the idea of playing with Anon, Soyo is delighted to help her out. Now with Soyo by her side, Anon's dream of forming a band is within reach—if only she could find a few more members.

Kaede Komura is in love. After being seated next to the airheaded Ai Mie for the past three days, Komura cannot help but be attracted to his bespectacled classmate. Although he has yet to have a proper conversation with Mie, Komura dreams of the day when she will look his way. One day, Komura notices that his seatmate is not wearing her glasses, learning by questioning Mie that she forgot them and has a tendency of doing so. When he sees her struggle, a concerned Komura takes it upon himself to help his crush. As the boy offers his assistance to Mie day by day, her reasons for constantly losing her glasses slowly evolve from the answer she initially gave.

During a school trip, a bus full of students is suddenly transported to another world by a sage named Sion. She bestows most of the students with powers called Gifts, seeking to recruit them to become sages as well. However, a few are excluded from receiving a Gift, resulting in the others leaving them behind. Yogiri Takatou, one of the students who did not receive a Gift, wakes up to find a dragon attacking the bus. Amidst the chaos, he executes the dragon using his innate ability to instantly put anything to death. Alongside fellow survivor Tomochika Dannoura, Takatou sets out to find a way back to Earth, all while eliminating anyone who dares to underestimate him—including his former classmates.