Touya Mochizuki grows accustomed to his new life in another world. Armed with his trusty smartphone, the teenager accepts small quests at his leisure while spending time with his new fiancées: Yumina Urnea Belfast, Yae Kokonoe, and twin sisters Linse and Elze Shileska. But even in a relaxing environment, Touya is only beginning to understand the responsibilities that come with these engagements. In addition to his romantic woes, the elder fairy Lean wishes to locate the remaining pieces of Babylon, the floating island that the mysterious Professor Regina Babylon created five thousand years ago. Touya reluctantly accepts her request and seeks out the teleportation circles that will lead to the islands. However, strange monsters have emerged—possibly powerful enough to destroy the world. In order to save the second life he was given, Touya must weaponize ancient technologies to fight these monsters—all while balancing his overwhelming number of relationships.

After the demise of the demon king, the resulting power vacuum has broken the balance of the world. Eager to claim this power for themselves, self-proclaimed demon kings from various worlds assemble in the New Principality of Lithia to fight for it. Among them, master swordsman Soujirou Yagyuu seeks to take this coveted position for himself. Joined by Tooi Kagizume no Yuno, a young girl he saved from an army of golems that destroyed her city, Soujirou enters Lithia to battle his way to the title. At the same time, the leaders of the Aureatia Kingdom seek to destabilize Lithia by launching bandits after the convoys of merchandise transiting through the principality. Enraged, Imashime of Taren, the founder of Lithia and defector from Aureatia, sends vicious thief Kasasagi no Dakai to investigate the origin of these attacks. With war on the brink of eruption, no one can predict what influence the contenders for the demon king's throne will have on the coming conflict.

World-class medical researcher Kanji Yakutani lost his little sister to a tumor years ago due to ineffective treatment. To honor her legacy, he has dedicated his research to developing new medications for such conditions. But as fate would have it, he overworks himself and passes away at the age of 31, only to be given a second chance at life in another world. When he wakes up, Kanji finds himself in the body of a 10-year-old boy named Falma de Médicis, the son of an esteemed family of medical practitioners in the Sain Fleuve Empire. Bearing the mark of a deity's divine blessing, Falma is capable of performing a unique divine art, allowing him to create and reduce any substance with the knowledge of its chemical properties. After reading through some pharmacology books, Falma realizes that this world is operating on similar medical practices as in ancient times. He also learns that medicine is an exclusive privilege to the nobility, depriving commoners of proper medical care. Using the knowledge from his past life and the divine abilities granted to him, Falma resolves to make medicine available to those who need it—irrespective of class.

The Joker and his best girl, Harley Quinn, are tearing through the streets of Gotham with sacks full of cash and the law in hot pursuit. Unfortunately for them, though the jester manages to escape, the night ends with Harley being captured by a mysterious, katana-wielding woman. Meanwhile, Amanda Waller, the head of the government security organization A.R.G.U.S., has commandeered a team of supervillains for a ruthless mission into another world. After losing contact with the first suicide squad sent through the portal, Amanda sends Deadshot, Peacemaker, Clayface, King Shark, and Harley as replacements. However, shortly after entering the portal, their helicopter crashes in the middle of a battle between horse-mounted troops and vicious orcs. With all of the accompanying A.R.G.U.S. members dead on impact, the villains break free of their shackles and rampage through the army of orcs, unwittingly aiding the human soldiers—only to be rewarded with imprisonment. Now bound by magic-infused shackles, Harley and company must hurry back to the portal they came from, or else the bombs A.R.G.U.S. implanted in their necks will detonate.