In the world of Duel Monsters, a new generation of duelists await their turn to bid for the highest title: The King of Games. As an aspiring duelist, the happy-go-lucky Juudai Yuuki enrolls at the Duel Academy, a reputable institution tasked with nurturing these potential challengers. On his first day, however, Juudai's laid back and careless attitude causes him to arrive late to his entrance exam. There, he stumbles upon a familiar figure who entrusts him the Winged Kuriboh, a card which becomes Judai's new partner. Soon, he begins living as a duelist—but will destiny and darkness bend his reality into something beyond his imagination? Yu☆Gi☆Oh!: Duel Monsters GX follows the story of Juudai as he strives to fulfill his goal of becoming the next King of Games. As they are thrust into countless unprecedented circumstances, one thing is for sure for Juudai and his friends—there will never be a dull moment at the Duel Academy!

After defeating a mysterious enemy, Yuuma Tsukumo, along with the help of Kaito Tenjou and Ryouga Shark Kamishiro, has thwarted the Barians' plans. However, Yuuma is still on a quest to retrieve the Number Cards to restore Astral's memories. The Seven Barian Emperors catch wind of Yuuma and Astral's endeavors and begin to collect the cards themselves to achieve their ultimate goal: destroying Astral's world in exchange for saving their own. Though only five of the emperors are present, they unanimously decide on annihilating Astral and Yuuma once and for all. Elsewhere, with their newfound powers of ZEXAL, Astral and Yuuma work to eliminate the enemy force that threatens Earth and the rest of the universe. Yu☆Gi☆Oh! Zexal Second unveils the mysteries and unpleasant surprises that lie in the wake of Yuuma's adversities. As Astral struggles to accept his past and the consequences it may have brought, will the gods continue to shower their fortune upon Yuuma on yet another perilous adventure?

The world of Duel Monsters is once again evolving with the development of a network called Link Vrains and a new summoning mechanic introduced as Link Summoning. By using this cyberspace, duelists can now create their own avatars and duel their way to glory within a virtual reality. However, much like the real world, the digital world is not free from war, conflict, and mysteries. Years ago, a hacker organization known as the Knights of Hanoi unleashed an attack on Link Vrains. Led by the anonymous Revolver, their aim was to annihilate the artificial intelligence program known as the Cyberse. After a failed attempt, one of their targets, Ignis, managed to escape and hide the Cyberse somewhere in the network. Five years later, high school student Yuusaku Fujiki encounters a strange artificial intelligence program while dueling in Link Vrains. Under the guise of his avatar named Playmaker, Yuusaku and his partner in crime, Shouichi Kusanagi, decide to join forces with the peculiar existence. As he seeks the truth behind a mysterious incident of the past, Yuusaku battles against the Knights of Hanoi and SOL Technologies in a race that might alter the fate of the world.

Yuugi Mutou is a naïve and lonely high school student who is fascinated by games. While staying with his grandfather, the owner of a game shop, he comes across an ancient Egyption relic known as the Millennium Puzzle. Rumored to grant any wish to those who solve the Puzzle, Yuugi becomes determined to solve it to wish for some friends. After years of struggling, Yuugi manages to complete the puzzle and mysteriously finds that his wish has been fulfilled. Meanwhile, a new card game known as Duel Monsters starts rising in popularity. In this game, players called duelists fight against each other with monsters by using magic and trap cards to foil their opponent's plans. Yuugi quickly becomes skilled at the game and lives a peaceful life with his newfound friends. However, Yuugi's peace is short-lived. The undefeated duelist and egocentric billionaire Seto Kaiba suddenly abducts Yuugi's grandfather, forcing him to duel against the rare Blue Eyes White Dragon'' card. Yuugi is thrown into a new world of fierce battles and the stakes continue to rise as dark forces interfere from the shadows. After unexpectedly defeating Kaiba with the help of his other self—the spirit of a nameless pharaoh—contained in the puzzle, he unofficially becomes the top duelist known as The King of Games. However, this new title will attract covetousness and Yuugi will have to use all his intelligence and willpower in order to protect what he holds the dearest to him.