Life seems simple for Koichi, a young student, until he learns that he is the reincarnation of an alien protector who crashed onto the mantle of responsibility asdefender of the Earth, Koichi/Babel teams up with a trio of super-powered alien companions to battle the the dark forces of an evil cult leader. The war to save humanity takes Babel from the deserts of southern Asia to the upper east side of Manhattan and ultimately to a final showdown with the master in a hidden base nestled in the Swiss Alps. The action is fast-paced and deadly. The fate of the world rests in the ability of this courageous youth to tame his latent psychic power and use it to defeat the enemies of mankind. (Source: AnimeNfo)

At the Ministry of Science, fervent Professor Ochanomizu alongside his coworkers strive to reactivate Atom—the first robot with a human heart. Atom is the masterpiece of enigmatic Professor Umatarou Tenma, who built the android to replace his deceased son Tobio. However, while Tenma inexplicably shut down his brainchild and disappeared, Ochanomizu refuses to let such a major breakthrough in science go to waste. Despite having the appearance of a nine-year-old, Atom not only possesses incredible strength and intelligence, but he is also endowed with a remarkable conscience and compassion that rivals humans. Sadly, the mechanical boy soon faces rejection and learns that not everyone is as welcoming as Ochanomizu. Although automatons have integrated into society, they are accepted only as tools and even seen as an upcoming threat to mankind's dominion. Dreaming of a world where people and robots can prosper together, Atom dedicates his existence to protecting the lives of both and inspiring them to form genuine bonds.

Shou Zama is an ordinary 18-year-old from Tokyo who finds himself summoned to the medieval fantasy world of Byston Well. Upon arrival, he is put into service under the ambitious lord Drake Luft, who seeks to greatly expand his power. Those like Shou who come from Upper Earth possess strong aura power and are ordered to pilot Aura Battlers, insectoid mecha designed by a man named Shot Weapon, who also came from Upper Earth. However, Shou's alliances quickly change when he meets Marvel Frozen, a young woman who has decided to rebel against Drake's political agenda. As he realizes the lord's true intentions, the boy chooses to join the fight against Drake and team up with Neal Given, who leads the resistance movement. The resistance isn't alone—Riml, daughter of their enemy and Neal's secret love, aids their efforts, hoping to escape from her father's clutches. As Shou finds himself fighting alongside his new comrades, they put their lives on the line to prevent the villainous Drake from taking over Byston Well before it's too late.

Natsume Tomoharu is a normal high-school student in every way with one exception: he's being followed by the ghost of his best friend, Misao. After moving into his brother's old house, Tomoharu expects to continue living his normal life but is one day left with a mysterious and locked briefcase without any instruction. At first he plans to leave it in storage; however, his house is soon invaded by multiple groups of people after the briefcase. Although still not knowing the purpose of the briefcase, Tomoharu and Misao attempt to escape with it. From there on, Tomoharu tries to learn the secrets behind the briefcase, the connections between it and Misao, and why it has the power to change the world.