Having been best friends since middle school, Haruka Takayama and Yuu Sonoda plan to attend Misato West High School together. However, despite being assigned to the same class, a cruel twist of fate has them seated on the opposite ends of their classroom! To make matters worse, their school will shut down in three years, making them the final intake of first-year students. Undeterred by this chain of unfortunate events, Haruka is set on sticking with Yuu, striving to create many wonderful memories with her. Much to Haruka's jealousy however, Yuu's easygoing demeanor quickly attracts the attention of their female classmates. Sympathizing with her friend's growing insecurity, Yuu ends up sharing a deep, affectionate kiss with her in an empty classroom. The act intensifies their bond as special friends, gradually revealing a different aspect to their unique friendship while also inviting new conflicts.

Kouta Hasegawa is a completely normal high school student who likes his Pompompurin stuffed animal, a Sanrio character modelled after a Golden Retriever, which his grandmother gave him when he was young. However, an incident in which other kids accused him of being girly for liking Sanrio characters made him ashamed of his attachment to Pompompurin. Through a series of unexpected events, Kouta ends up meeting others at school who also like Sanrio characters—Yuu Mizuno, a flashy boy who is popular with girls; Shunsuke Yoshino, a member of the soccer team; Ryou Nishimiya, an underclassman who is a library assistant; and Seiichirou Minamoto, the student council president. Through his new friends, Kouta learns that there is no need to be embarrassed for liking Sanrio characters; and together, they aim to create a play for the cultural festival in order to transform his normal school life into a sparkly one.

Yoshikazu Miyano's troubles first start one hot summer day when Shuumei Sasaki steps into his life. Sasaki saves Miyano's classmate from a group of bullies, and after that, Miyano cannot seem to shake off his eccentric upperclassman. His silent admiration for Sasaki gradually sours into annoyance each time the so-called delinquent refuses to leave him alone. Constantly being called by cute nicknames and having his boundaries ignored, Miyano wonders why Sasaki wants to get close to him. The shy and easily flustered Miyano harbors an embarrassing secret—he is a fudanshi, a boy who likes boys' love (BL) manga. The last thing he wants is for other students to find out, but through a slip of the tongue, he reveals the truth to Sasaki. Intrigued, the clueless Sasaki asks to borrow a book to read, which he is given very reluctantly. To Miyano's surprise, Sasaki enjoys the BL that he receives and asks for more, marking a shift in their strange dynamic. Although Sasaki appears to possess some personal agenda, his feelings for Miyano become complicated the more time they spend together. As they now share a common interest, their relationship is poised to change and further develop.

The Japanese call them hikikomori—people who've become so withdrawn socially that they refuse to leave their homes for weeks and even months at a time. For Sasami Tsukuyomi, who's attempting to pass her first year of high school despite being a shut in, it's more than just a word. Fortunately though, she lives with her older brother Kamiomi, who just happens to be a teacher at the school Sasami is supposed to attend. Not to mention, her Brother Surveillance Tool which lets her view the outside world via her computer and will, theoretically, allow her to readjust to interfacing with people again. What it mainly does, however, is let her view her brother's interactions with the three very odd Yagami sisters, who inexplicably seem to have had their ages reversed and have various types of interest in Kamiomi. And then things start to get really weird... Magical powers? Everything turning into chocolate? Is life via the web warping Sasami's brain, or is it the universe that's going crazy? (Source: Sentai Filmworks)