Haneda Takashi has a secret he cannot speak of. To leave his dull school-life, he was supposed to have escaped to another world. However, he is reeled in by certain ties on his heart. One of these is Kobato, his awkward younger sister. The other is Watarai Asuka, his negligent girlfriend. Chitose Shuusuke is a poor freeloader. He passes his days working at various part-time jobs. One day, he has a disastrous first encounter with Tamaizumi Hiyoko. The next time they meet, Shuusuke discovers that they are fellow employees at his part-time job. Narita Hayato sees himself as a hard-boiled person. Back-breaking jobs are nothing to him. Hayato shuns normal human contact, but, during the nights, he would get together with delinquents and other denizens of the night. One such night, he meets the cheerful and oblivious Otori Naru. The relationships with these girls will greatly affect these 3 young men. But what, exactly, is the relationship these young men have with each other? (Source: AnimeNFO)

The diehard otaku Kirino Kousaka has returned and settled back into life in Japan with her friends and family. Despite what her older brother Kyousuke has previously done for her, Kirino continues to give him the cold shoulder, much to his frustration. He is worried that his persuasion for Kirino to drop her track and field training in America and return home may have severely strained his relationship with her. On top of that, Kyousuke now also has to decode a bold and cryptic message from Ruri Kuroneko Gokou, his junior at school as well as Kirino's friend. As the ties between the two siblings and their friends deepen, Kirino and Kyousuke will soon have to figure out how they want to deal with these relationships, helping each other realize their own feelings in the process. In spite of that, Kirino still manages to find time to satisfy her otaku needs with the company of her brother.

Chisato Mizusawa is a calm and collected assistant office manager who apparently dislikes drinking alcohol. But she actually likes it and has a secret side to her that emerges only when drunk: her cute persona, which she only reveals to her husband, the bartender Sora. Each day when Chisato comes home, Sora takes care of his beloved wife, providing her with a good meal and a fresh drink. These drinks include Plum Splet, Irish Coffee, Orange Breeze, and many more tasty concoctions that she eagerly gulps down. But as much as she likes alcohol, she loves her kindhearted husband more. Together, they share a life that is filled with happiness—and the more-than-occasional cocktail.

Mahiru Shiina is worthy of her nickname Angel: she is a divine beauty loved by all, and she excels in both academics and athletics. Shiina lives in an entirely different world from Amane Fujimiya, her next-door neighbor. Despite living so close together, they have never spoken once. But their silence is broken when Fujimiya spots Shiina gloomily sitting on a swing amidst a heavy rainstorm and lends her his umbrella. When Fujimiya catches a cold the next day, Shiina wishes to return the favor for the umbrella by nursing him back to health. Believing that this would be their first and last interaction, he silently appreciates her kindness. However, Shiina—who cannot help but worry about Fujimiya's lack of tidiness and proper nutrition—begins to cook and clean for him. As the unlikely pair spend time together in Fujimiya's apartment, they explore the true nature of their relationship and the gentle emotions that emerge from it.