The story follows Kintaro, former leader of a widely feared and respected biker gang, who decides that its time to straighten out and become a salaryman since his wife died and he has to take care of his young son. (Source: AniDB)

In the far distant future, on a planet that might have been called earth, there was a war between samurai who mechanized their bodies. After the long war, people enjoyed a modest peace. Facing starvation and abductions at the hands of fearsome mechanized bandits (Nobuseri), the farmers of Kanna Village make the dangerous choice to hire samurai for protection. The village's water priestess, Kirara, her younger sister, Komachi, and a heartbroken villager, Rikichi, set off to hire willing samurai with nothing to offer but rice from their meager harvests. Through dangerous encounters and a bit of luck, seven samurai of varying specialties and experience are gathered for an epic battle against the bandits and the merchants that influence them. Samurai 7 is based loosely upon Kurosawa Akira's famous movie Seven Samurai/Shichinin no Samurai

Kei Asai lives in the oceanside city of Sakurada—a town where the inhabitants are born with strange abilities. On the school rooftop one day, he meets Misora Haruki, an apathetic girl with the power to reset anything around her up to three days prior. While no one knows when she has reset, not even Haruki, Kei can retain everything before the reset thanks to his own ability: photographic memory. After they successfully help someone by combining their powers, they join the Service Club to aid others in their town. However, their club becomes involved with and begins completing missions for the mysterious Administration Bureau—an organization that focuses on managing the abilities in Sakurada and manipulating the town's events for their own ends. They may find out that there are more things at work in Sakurada than the machinations of the uncanny organization.

At Suimei High, the Sakura-sou dormitory is infamous for housing the school's most notorious delinquents. Thus, when the relatively tame Sorata Kanda is transferred to the dorm, escaping this insane asylum becomes his foremost goal. Trapped there for the time being, he must learn how to deal with his fellow residents, including bubbly animator Misaki Kamiigusa, charming playboy writer Jin Mitaka, and the ever-reclusive Ryuunosuke Akasaka. Surrounded by weirdness, Sorata frequently finds respite in his interactions with his one normal friend, aspiring voice actress Nanami Aoyama. When Mashiro Shiina—a new foreign exchange student—joins the dormitory, Sorata is instantly enraptured by her beauty. Underneath her otherworldly appearance, Mashiro is an autistic savant, capable of world-renowned brilliance in her art, yet unable to perform simple daily tasks. After Sorata ends up in charge of taking care of Mashiro, the two inevitably grow closer, with Sorata's initial desire to escape the dormitory becoming a forgotten goal. Despite their eccentricities, every resident is incredible in their own field, leaving Sorata to contend with his own lack of any particular skill. With brilliance all around him, he thus strives to become an equal to their talent. Revolving around the hardships and joys of its colorful cast, Sakura-sou no Pet na Kanojo is a heartwarming coming-of-age tale of friendship, love, ambition, and heartbreak—through the lens of an ordinary person surrounded by the extraordinary.