Traumatized by school, Jun Sakurada spends his days at home as a shut-in, purchasing things online, only to send them back before the free trial period ends. So when a note appears on his desk, asking whether or not he would wind something, he assumes it was something he ordered and carelessly circles yes, changing his life forever. A box arrives with a wind up doll inside, but this is no ordinary toy: after Jun winds her up, she begins walking and talking as if a normal person. With a haughty attitude, she introduces herself as Shinku, the fifth doll in the Rozen Maiden collection, a group of special dolls made by the legendary dollmaker Rozen. These sisters must battle each other in a competition called the Alice Game with the help of a human to ensure victory. The winner becomes Alice, a real girl who is worthy of meeting their creator. As more sentient dolls end up taking residence in Jun's house, and a foe from Shinku's past makes her appearance, Jun's life becomes far more complicated than he ever thought possible.

During the events of the original Rozen Maiden, after circling yes on a paper and agreeing to wind an unknown something, a traumatized Jun Sakurada fights alongside the lifelike dolls known as the Rozen Maidens. But what would have happened if Jun had circled no? Jun, having gotten over his school trauma from his younger days, spends his time attending college and working in a bookstore. However, he does not feel as though he belongs anywhere. One day, he finds a book containing instructions on how to make a Rozen Maiden. Mysteriously, when he arrives home that night, the second volume in the book series has been delivered to his house, along with some pieces of a doll. But as suddenly as they started arriving, the books stop coming, and Jun gets a notice that says that the books have ceased being published. With an incomplete doll in hand, and a message from his other self in another world, this Jun also finds his way into the world of the Rozen Maidens.

It has been one year since Tsukune Aono enrolled at Youkai Academy, and since then his life has taken an interesting turn. In addition to being the only human at a school for monsters, he has attracted a bevy of beautiful women who want him all for themselves: the sexy succubus Kurumu Kurono; Yukari Sendou, a witch; stalker and yuki-onna Mizore Shirayuki; and Moka Akashiya, a kind vampire who, when her rosary is removed, reveals a darker personality. But soon, trouble visits Youkai Academy in the form of Moka's younger sister, Kokoa Shuzen. She is furious that her true older sister is sealed within Moka's rosary, and vows to bring out Moka's darker self. However, Kokoa's thoughtless actions may affect more than just her sister...

The adventure of Hepoi, a hero of heporis, Ryuuto, the prince of Dragonia, Miiya Miiya a fairy looks like a cat, and Bunzaemon, a merchant, to defeat Dracunes, the King of dark side castles.