Tenchi Masaki's life changes forever when the ship of an infamous space pirate, Ryouko Hakubi, is shot down and crashes near his family's temple. Little did Tenchi know that by saving Ryouko, he would spark a series of events that would lead alien women from all walks of life to inhabit his home. This includes the delicate Princess Aeka of Jurai and her playful younger sister Princess Sasami; the scatterbrained first-class detective Mihoshi Kuramitsu and her more capable partner Kiyone Makibi; and the eccentric, mad scientist Washuu Hakubi. The six women do their best to adapt to their new lives, but their more advanced and exotic lifestyle does not mesh well with the simplistic customs on Earth. As a result, they just end up making a mess and causing trouble for poor Tenchi. Though the girls are a pain, Tenchi begins to form a close relationship with each of them, and through their bond, he begins to gain a better understanding of his role in the universe.

In the beginning, God created the heavens and the earth. He also sought after a wide variety of animals to populate the planet. However, he felt that it was too tiresome to think of new ideas within his criteria. To address this problem, God appointed an organization—the Heaven's Design Team—to do the work instead! Shimoda is a newly-hired angel who serves as the mediator between God and the design team. As he steps into his role, he witnesses his coworkers conceive interesting ideas for many unique life forms according to God's desires. From giraffes and snakes to birds, anteaters, and everything in between, the possibilities for different animal species are endless!

Fifteen years ago, disaster struck human civilization, and now dangerous man-eating monsters roam the ravaged lands, posing an existential threat to the remaining survivors. Amid this turmoil, an isolated facility shelters children and nurtures them in peace. However, as a few among them find out about the world beyond the narrow periphery of their nursery's walls, their curiosity about it slowly grows. Meanwhile, in the outside world, young survivors Maru and Kiruko band together to search for a special place called Heaven, each for their own reasons. Carrying past burdens and tragic secrets, the two hope to find answers to the cruelty they have experienced in their lives and in the world, which still remains in tatters.

In the year 1930, vampires have infiltrated Tokyo to feast upon its unsuspecting citizens. As the number of victims continues to rise, the city's authorities decide to hire the Jaegers—a strange, diverse group of individuals tasked by the V Shipping Company to hunt down vampires around the world. Carrying musical instrument cases to disguise their identity, the Jaegers battle the vampires with the same mercilessness demonstrated by their foes. Yuliy, the Jaeger's most skilled warrior, is the sole survivor of a vampire raid on his home village. Using the strength granted by his werewolf blood, he works with his team to assist Tokyo's law enforcement with the city's vampire problem. Though under the pretense of helping the police, the Jaegers are actually fighting the vampires over the mystical Ark of Sirius. With its power to change the fate of the world, Yuliy and his friends must locate the artifact before the vampires can use it to achieve their destructive goals.