A mysterious attacker has appeared and is assaulting people whose names contain a number from the standard deck of cards in descending order. When Conan Edogawa points out that all the victims are related to the now famous detective Kogorou Mouri, suspicion immediately falls upon the recently released convict Jou Murakami, as Kogorou was the one responsible for his arrest ten years prior. With potential victims still at risk, Conan and the police are determined to catch the culprit. As the case gradually unfolds, both Conan and his friend Ran Mouri learn more about her parents' separation and the truth on what transpired a decade ago.

Once again, Kaitou Kid crosses swords with Conan Edogawa in this annual installment of the Detective Conan movie franchise. After receiving a letter from the thief, famous actress Juri Maki seeks the help of private detective Kogorou Mouri to protect the Star Sapphire—the Jewel of Destiny, said to represent faith, fate, and hope. Thinking he has deciphered Kid's riddle, Kogorou personally shows up to the newly constructed space theater where Juri is acting in the play Josephine in order to catch Kid in the act. The next day, Conan and the gang are invited by Juri to her holiday home, to celebrate the thwarting of Kid's plan and the success of the play. However, their triumph crumbles when a murder occurs during the flight there. Although unintentional, this sets off a series of events that escalate to catastrophic results. Conan and Kid, unlikely allies that they are, must work together to save both their friends and every other passenger aboard the plane.

Fudo Jun is a beautiful supermodel who is idolized by many. She also has a dark secret that not even she knows about at first, for within her veins run the genes that hold the next step in the evolution of mankind. The same blood as the beastlike superhumans that terrorize the city. Unlike the rest of them, though, Jun has managed to hold a tenuous grip onto her humanity, and she is recruited by the mysterious Asuka Ran, member of a secret organization within the government, aimed at controlling, if not eliminating, these berserk destroyers of mankind. Jun, as Devilman Lady, must now exterminate her own kind, but how much longer can she keep her sanity in a situation she never chose in the first place? (Source: ANN)

A recap episode with additional scenes which was screened on Jump's official YouTube channel for Jump Special Anime Festa 2020.