Shinichi Chiaki is a first class musician whose dream is to play among the elites in Europe. Coming from a distinguished family, he is an infamous perfectionist—not only is he highly critical of himself, but of others as well. The only thing stopping Shinichi from leaving for Europe is his fear of flying. As a result, he's grounded in Japan. During his fourth year at Japan's top music university, Shinichi happens to meet Megumi Noda or, as she refers to herself, Nodame. On the surface, she seems to be an unkempt girl with no direction in life. However, when Shinichi hears Nodame play the piano for the first time, he is in awe of the kind of music she creates. Nevertheless, Shinichi is dismayed to discover that Nodame is his neighbor, and worse, she ends up falling head over heels in love with him.

In ancient Disboard, Riku is an angry, young warrior intent on saving humanity from the warring Exceed, the 16 sentient species, fighting to establish the One True God among the Old Deus. In a lawless land, humanity's lack of magic and weak bodies have made them easy targets for the other Exceed, leaving the humans on the brink of extinction. One day, however, hope returns to humanity when Riku finds a powerful female Ex-Machina, whom he names Schwi, in an abandoned elf city. Exiled from her Cluster because of her research into human emotions, Schwi is convinced that humanity has only survived due to the power of these feelings and is determined to understand the human heart. Forming an unlikely partnership in the midst of the overwhelming chaos, Riku and Schwi must now find the answers to their individual shortcomings in each other, and discover for themselves what it truly means to be human as they fight for their lives together against all odds. Each with a powerful new ally in tow, it is now up to them to prevent the extinction of the human race and establish peace throughout Disboard.

The carefree journeys of the four girls continue! As their fleeting yet eventful summer becomes a distant memory, the arrival of fall signals a new school year with limitless opportunities. Even as the four girls return to their peaceful routine, the appearance of new faces enlivens the anything but exciting rural life of Asahigaoka. Non Non Biyori Nonstop leisurely walks back into the lives of Hotaru Ichijou, Komari Koshigaya, Natsumi Koshigaya, and Renge Miyauchi as they fully embrace their rural lifestyles and turn anything they find into nothing but fun!

While spending a summer day at the department store, Suguru Koshigaya wins the lottery’s grand prize—four tickets to Okinawa! Filled with awe and excitement, the girls of Asahigaoka do various things to prepare for the trip. From practicing how to ride on an airplane to buying travel essentials at the convenience store, they do everything beforehand so they can enjoy their time in Okinawa to the fullest extent. A departure from the familiar scenery of Asahigaoka is a new experience for Renge Miyauchi, but that does not stop her from pondering how her perspective of the world may change. As the day of the trip draws near, a promise is made.