Ichigo Momomiya is excited to start high school and fall in love. She is in luck when she meets the popular and good-looking Masaya Aoyama, and she immediately develops a crush on him. When Ichigo learns that Aoyama is passionate about the environment, she seizes the chance to ask him out thanks to some tickets to an exhibition about endangered animals. During their date, Ichigo is struck by a mysterious light and faints. Waking up to the sight of Aoyama, she remains unharmed—but they both must escape from a giant rat-like creature after it injures Aoyama. To save her crush, Ichigo awakens her powers and transforms into a heroine with the skills of a cat. After she defeats the monster, researchers Ryou Shirogane and Keiichiro Akasaka explain that Ichigo was chosen to become a part of the Mew Project: a group of five magical girls whose DNA has been infused with those of certain endangered species. Now, Ichigo must find the rest of her teammates to defeat the Chimera Anima—beings infected by aliens who want to take over the world—before it is too late.

When a sudden thunderstorm strikes, Mei, a young goat, has no choice but to take shelter in an abandoned barn. Before long, he is joined by another animal—a wolf named Gabu. The night is pitch black, and neither of them can make out the other's appearance, but they become fast friends as they chat for hours, promising to meet again. As soon as Mei and Gabu reunite in daylight, they are met with a predicament: they would normally regard each other as mere predator and prey. However, they vow to remain friends nonetheless and start meeting in secret. While their friendship deepens, their families find out about it, forcing both Mei and Gabu to wonder if their relationship is truly worth the risk.

15 one-minute shorts created by various people from Japan's animation industry. The title of the collection, Ani*Kuri15, is abbreviated from the words anime and creators. Season One Shinji Kimura (Studio 4°C; Art Director, Steamboy) - title: Attack of Higashimachi Ni Chome/Attack of Higashimachi 2nd Burough Shōjirō Nishimi (Studio 4°C; Character Designer, Tekkonkinkreet) - Uchujin Raikou Hiroshi no Baai/Invasion from Space - Hiroshi's Case Akemi Hayashi (Gainax; Character Designer, Fruits Basket) - Namida no Mukou/From the Other Side of the Tears Osamu Kobayashi (Madhouse; Art/Mecha Desgin, Gungrave) - Sancha Blues/The Aromatic Tea Blues Yasufumi Soejima (Gonzo; 3D/CG Director, Last Exile) - Hyotoko/Blaze Man Season Two Atsushi Takeuchi (Production I.G; Mecha Design, Ghost in the Shell) - Wandaba Kiss Mamoru Oshii (Production I.G; Director, Ghost in the Shell) - Project Mermaid Kazuto Nakazawa (Studio 4°C; First Unit Director, Kill Bill Chapter 3: The Origin of O-Ren from Kill Bill: Volume 1) - yurururu ~Nichijou Hen~ Ranji Murata (Gonzo; Character Design, Blue Submarine No. 6) and Tatsuya Yabuta (Gonzo; Story Design, Final Fantasy VII) - Gyrosopter Tobira Oda (Original Manga, Danchi Tomō) and Yasuyuki Shimizu (Key Animation, Naruto (movies)) (Studio 4°C) - Supaatsu Taisa/Colonel Sports Season Three Michael Arias (Studio 4°C; Director, Tekkonkinkreet) - Okkakekko Makoto Shinkai (Comix Wave Film; Director, The Place Promised in Our Early Days) - Neko no Shuukai/A Gathering of Cats Shōji Kawamori (Satelight; Director, The Super Dimension Fortress Macross: Do You Remember Love?) - Project Omega Mahiro Maeda (Gonzo; Director, Gankutsuou: The Count of Monte Cristo) - Onmitsu Hime/Princess Onmitsu Satoshi Kon (Madhouse; Director, Paprika) - Ohayō/Good Morning

As novelist Fuji is returning home in a rainstorm, her attention is caught by something peculiar: an animal resembling a dog asking her to take it in. Although she is reluctant at first, the animal impresses her by handing her an umbrella, resulting in Fuji welcoming the creature into her apartment. Soon, Fuji realizes that the animal is even smarter than she initially thought, as it begins communicating with her through writing. Whether the two are alone or hanging out with her family and friends, Fuji's new little friend never fails to entertain with its whimsical actions.