On a fateful summer night in 2006, Mutta Nanba and his younger brother Hibito witness what they believe to be a UFO flying toward the Moon. This impressing and unusual phenomenon leads both siblings vowing to become astronauts, with Hibito aiming for the Moon and Mutta, convinced that the eldest brother has to be one step ahead, for Mars. Now an adult, life hasn't turned out how Mutta had pictured it: he is diligently working in an automotive company, whereas Hibito is on his way to be the very first Japanese man to step on the Moon. However, after losing his job, Mutta is presented with an unexpected opportunity to catch up to his younger brother when the Japanese Aerospace Exploration Agency, commonly known as JAXA, accepts his application to participate in the next astronaut selection. Despite self-doubts about his prospects, Mutta is unwilling to waste this chance of a lifetime, and thus embarks on an ambitious journey to fulfill the promise made 19 years ago.

The world of Auldrant is bound by the Score, a series of prophecies from centuries past that dictate the world's future. It is considered an absolute fate that everyone lives by—even people whose actions lead to bloodshed and tears. Using magical abilities known as the Fonic Arts, a war between the nation of Kimlasca-Lanvaldear and the Malkuth Empire is waged in hopes of bringing the Score's foreseen utopia to life. Tales of the Abyss follows Luke von Fabre, who spends his days locked away in his manor after being kidnapped and losing memories as a child. One day, while honing his swordsmanship, a woman named Tear attempts to assassinate his master. Luke defends him, but the clash results in the two being teleported to a distant land. Luke and Tear’s journey back quickly escalates into a quest that will either free the world from the Score's chains or destroy it completely.

The year is 2065, and the planet of Earth is far removed from the place that it was in the past. Deadly alien creatures known as Phantoms have appeared all over the planet, and mere contact with these entities is lethal, whether it be an instant death or a prolonged decline. In order to try and salvage what little of the human race is left, large force-field barriers have been constructed around certain cities to repel the Phantoms. Seeking a more permanent solution to this invasion are scientists Aki Ross and her mentor, Dr. Sid, whose investigations have revealed that there exists a form of spiritual, Gaia energy that can eradicate the Phantom's presence from this world. Aki and Sid aren't alone in their quest through Final Fantasy: The Spirits Within; the human council and the military squad Deep Eyes are ready to help. Not everyone is convinced of this plan though. Aki, Sid, Grey, and their allies have to band together against forces both alien and human if they are to have any chance at restoring peace to Earth. An enemy whose mere touch is fatal, the Phantoms appear the more dangerous enemy, but as they will come to find out, their human nemeses are also not to be trifled with.

Loid Forger, an elite spy, is warned by his handler that he may potentially be reassigned from his ongoing mission, Operation Strix. To maintain his position, he must make significant progress toward the operation's objectives, which involves having his adoptive daughter Anya earn sufficient Stella Stars to become an Imperial Scholar at Eden Academy. After learning of a cooking contest that awards the winning student with a Stella Star, Loid researches the judge's preferred dessert to help increase Anya's odds. However, perfectly recreating the judge's favorite meremere requires more than just following a recipe. Thus, the Forgers embark on a vacation to the Frigis region to try an authentic meremere. Not all goes smoothly on the trip, as the Forger family ends up entwined in a sinister plot to reignite war between the countries of Ostania and Westalis.