Most people would prefer being the protagonist of a world full of adventure, be it in a game or in another world. But, unfortunately, a certain girl is not so lucky. Regaining the memories of her past life, she realizes that she was reborn in the world of Fortune Lover—one of the games she used to play. Unfortunately, the character she was reincarnated into—Catarina Claes—is the game's main antagonist, who faces utter doom in every ending. Using her extensive knowledge of the game, she takes it upon herself to escape from the chains of this accursed destiny. However, this will not be an easy feat, especially since she needs to be cautious as to not set off death flags that may speed up the impending doom she is trying to avoid. Even so, to make a change that will affect the lives of everyone around her, she strives—not as the heroine—but as the villainess.

Youto Yokodera wants to be seen in a way different from most men: as a pervert. However, his lewd actions are often misinterpreted as good intentions, and people cannot see his true nature. Upon hearing rumors of a cat statue that can banish an unwanted trait, he searches for it and prays for his façade to be removed. But each wish comes at a price: those unwelcomed traits are transferred to someone else who desires them! After realizing that vocalizing his dirty thoughts is not the best thing, Youto decides to regain his lost traits by seeking out the person who received them. Unfortunately, he was not alone in praying to the cat statue, and now he must not only fix his life, but the lives of others as well.

Ten-year-old Sakura Kinomoto is an ordinary fourth-grade student living in Tomoeda until, one day, she stumbles upon a mysterious book of cards titled The Clow. Pondering over her discovery, she unintentionally causes a magical gust of wind to scatter the cards all over town. The accident awakens the Beast of the Seal—Keroberos, nicknamed Kero—who tells Sakura that she has released the mystical Clow Cards created by the sorcerer Clow Reed. Due to each Card's ability to act independently and their incredible power, Clow had sealed them away. Now that they have been set free, the Cards pose great danger to the world, and it is up to Sakura to put an end to them. Appointing Sakura as the Cardcaptor and granting her the Sealed Key, Kero tasks her with finding and recapturing all the Clow Cards. Alongside her best friend Tomoyo Daidouji, and with Kero's guidance, Sakura must learn to balance her new secret duty with the everyday troubles as she takes flight on her magical adventures as Cardcaptor Sakura.

Kenjaku, the one known as Noritoshi Kamo and most recently as Suguru Getou, has initiated the next step in his destructive, thousand-year plan of ordinary humans' evolution and eventual eradication. The jujutsu world higher-ups reinstate 15-year-old Yuuji Itadori's execution, as Satoru Gojou is incapacitated as a result of Kenjaku's master plan in Shibuya. While Yuuji is unaware of this, he patrols the abandoned Tokyo streets with Chousou, exterminating any and all cursed spirits in his way. Meanwhile, the bigoted and arrogant Naoya Zenin's pride takes a hit when Megumi Fushiguro is selected as the Zenin Clan's next head. To draw out Megumi and eliminate him, he goes after Yuuji—but Yuuta Okkotsu is set on being Yuuji's executioner. Kenjaku's Culling Game—a rigorous battle royale spanning throughout Japan and forcing the jujutsu competitors to kill each other—is set in motion, and the young jujutsu sorcerers join the fray to settle old scores, free Gojou, and liberate the jujutsu world from the threat that is Kenjaku.