One day after school, first-year high school student Yomogi Asanaka comes across a starving man under a bridge. Introducing himself as Gauma, the strange drifter informs Yomogi that he is a kaiju user, a person who deals with the kaiju—monsters who bring harm to the city and its citizens. The following evening, Yomogi runs into Gauma and his classmate Yume Minami. Simultaneously, a kaiju appears in a populated area of the city. Due to Gauma's lack of experience controlling the kaiju, he brings out a mysterious object from a glowing pouch, summoning a giant robot known as Dynazenon. Requiring the cooperation of four people, the mecha drags Gauma, Yomogi, Minami, and Koyomi Yamanaka—an unemployed man who was wandering on the street—into its cockpit. Their encounter with the kaiju marks the beginning of their entanglement with kaiju eugenicists—kaiju users who manipulate kaiju with ill intent—and their efforts toward bringing out the full potential of Dynazenon.

Specials bundled with the 1st season's BD/DVD volumes.

In Vandread, men are from Mars and women are from Venus! Well, not quite. Technology has allowed mankind to colonize the entire Milky Way galaxy, and in one star system, the men and women live on two different planets, Taraak and Mejere. A bitter and very literal gender war rages, to the point where they don't even see each other as the sames species anymore! Hibiki Tokai, a male third-class laborer from Taraak, ends up stuck on a battleship after a botched attempt at stealing a robot. When female pirates capture the Taraakian Vanguard, things don't look like they could get any worse for Hibiki. Unfortunately, they do; when the male crew of the Vanguard fire on their captured vessel out of desperation, they created a giant wormhole, which sucks the Vanguard and the Mejeran pirate's ships into itself! Now, stuck far away from their home planets, these men and women must learn to work together if they ever wish to make it back home.

In the near future, augmented reality has become a key part of daily life. A gentle middle school girl named Yuuko Yasako Okonogi and her family have just moved to Daikoku City despite rumors of people disappearing. There, her grandmother, nicknamed Mega-baa, runs a shop called Megasia that specializes in illegal tools which interact with parts of the virtual world. Mega-baa also hosts an unofficial detective agency called Coil, a group of children around Yasako's age who find and handle corruption of the virtual world. Yasako gets involved with the group when Fumie Hashimoto, a playful member of Coil, helps rescue her cyberdog Densuke after getting trapped in virtual space while chasing a mysterious virus. Also investigating these corruptions and viruses is an abrasive hacker named Yuuko Amasawa, who the others take to calling Isako. Can Coil discover the truths behind the mysterious viruses and corruption, and if they can, at what cost?