The cells of the human body never rest for too long; there's always something new to do and learn every day. At least, that's what Hakkekkyuu U-1146 feels as he rushes to and fro, searching for any pathogens that could cause harm to the body. Despite his dangerous line of work, it's all worth it to protect the happy smiles of Sekkekkyuu AE3803, the platelet crew, his fellow neutrophils, and the other cells he meets along the way. In his latest pathogen-hunting adventures, Hakkekkyuu U-1146 discovers how important cells can sometimes make mistakes, and that not all bacteria are actually bad. Everybody has their bad days, but everything eventually works out when their comrades have their backs. In the end, it's just another normal day for these hardworking cells!

If you could turn all your memories into a song, what would it resemble? Between being an exceptional student and taking care of the house alone during her mother's absence, Asuna Watase's only distraction is listening to her old crystal radio in her secret mountain hideout. One day, she accidentally tunes to a mysterious and melancholic melody, different from anything she has ever heard before. Soon after, an enigmatic boy named Shun saves her from a dangerous creature, unknowingly dragging Asuna on a long journey to a long lost land bound to surpass her very imagination, turning her once melodic life into an intricate requiem.

Kino, a 15-year-old traveler, forms a bond with Hermes, a talking motorcycle. Together, they wander the lands and venture through various countries and places, despite having no clear idea of what to expect. After all, life is a journey filled with the unknown. Throughout their journeys, they encounter different kinds of customs, from the morally gray to tragic and fascinating. They also meet many people: some who live to work, some who live to make others happy, and some who live to chase their dreams. Thus, in every country they visit, there is always something to learn from the way people carry out their lives. It is not up to Kino or Hermes to decide whether these asserted values are wrong or right, as they merely assume the roles of observers within this small world. They do not attempt to change or influence the places they visit, despite how absurd these values would appear. That's because in one way or another, they believe things are fine as they are, and that the world is not beautiful; therefore, it is.

Haruka Nanami, an aspiring composer from the countryside, longs to write music for her beloved idol, Hayato Ichinose. Determined to accomplish this goal, she enrolls into Saotome Academy, a highly regarded vocational school for the performing arts. Upon her arrival, Haruka soon learns that everyone on staff, including the headmaster, is either an idol, a composer, or a poet. To top it all off, she is surrounded by incredibly talented future idols and composers, and the competition among the students is fierce; with the possibility of recruitment by the Shining Agency upon graduation, the stakes are incredibly high. As she strives to reach her dream at the academy, one fateful night, a series of events lead Haruka to a mysterious man standing in the moonlight, and he seems a bit familiar...