In the 24th century on the planet Aqua, three girls—Akari Mizunashi, Alice Carroll, and Aika S. Granzchesta—continue to work hard toward achieving their goal of becoming Prima Undines: professional tour guide gondoliers. Luckily, the girls have the guidance of the three best Prima Undines in Neo-Venezia—Alicia Florence, Athena Glory, and Akira E. Ferrari—who are known as the Water Fairies in honor of their skill. With their help, the young apprentices train hard and work to overcome any situations that they find themselves in. Aria The Origination follows the hardships and daily lives of these three young girls, who are doing their best to improve as tour gondoliers in Neo-Venezia, a terraformed replica of Venice.

The Labyrinth is an expansive space deep underground where humans live in clusters known as colonies. Over the years, the surface has become a distant memory—even perhaps only a fantasy to those who have never experienced its wonders. Making sure humanity survives the harsh conditions of the underground, a colony's citizens can take on a variety of specialized jobs. These include Workers, who mine precious ore to fuel the colonies, and Markers, who journey into the Labyrinth's surprisingly lush environment to bring back information that eases navigation. However, humanity also faces a threat to its existence—creatures called kaijuu whose sizes range from that of a small child to an enormous building, and are hostile to any human they see. Moreover, kaijuu that are large enough can force their way into the colonies, further increasing their threat level. Memenpu is a nine-year-old college graduate whose inventions have greatly benefitted the Workers in her local colony. Recently, however, she has been dreaming of a place with a neverending ceiling not bound by bedrock. These aspirations fuel her desire to become a Marker and explore the Labyrinth's vast unknown in search of such a fantastical place. Despite her father Gagumber's vehement disagreement, a certain incident with the kaijuu jumpstarts a dangerous yet exciting adventure that will surely alter humanity's course forever.

Fifteen-year-old Komori Shuri is a junior high school girl who is too nice to decline requests. Constantly doing favors for other people has given her incredible strength?! But even so, she is also an adolescent junior high school girl. An anime overflowing with the ups and downs of everyday life! (Source: Batoto, edited)

Hitomi Kanzaki is in a very depressed mood. She only wants to sleep and fade away. Her misery summons Lord Folken who sends her to Gaea. The people of Gaea think she is the Wing Goddess, who can call upon the legendary Dragon Armor called Escaflowne. On Gaea, King Van, the sole survior of the White Dragon Clan, is also in a depressed state. Swearing an oath to get his revenge on the Black Dragon Clan that obliterated Van's kingdom, he lives by the sword. Now that the Wing Goddess has finally appeared, she posseses Gaea's world fate in her heart. Escaflowne will either lead Gaea to peace or total ruin. (Source: ANN)