Aslan Jade Callenreese, known as Ash Lynx, was a runaway picked off the streets of New York City and raised by the infamous godfather of the mafia, Dino Golzine. Now 17 years old and the boss of his own gang, Ash begins investigating the mysterious Banana Fish—the same two words his older brother, Griffin, has muttered since his return from the Iraq War. However, his inquiries are hindered when Dino sends his men after Ash at an underground bar he uses as a hideout. At the bar, Skip, Ash's friend, introduces him to Shunichi Ibe and his assistant, Eiji Okumura, who are Japanese photographers reporting on American street gangs. However, their conversation is interrupted when Shorter Wong, one of Ash's allies, calls to warn him about Dino. Soon, Dino's men storm the bar, and in the ensuing chaos kidnap Skip and Eiji. Now, Ash must find a way to rescue them and continue his investigation into Banana Fish, but will his history with the mafia prevent him from succeeding?

Maomao, an apothecary's daughter, has been plucked from her peaceful life and sold to the lowest echelons of the imperial court. Now merely a maid, Maomao settles into her new mundane life and hides her extensive knowledge of medicine in order to avoid any unwanted attention. Not long after Maomao's arrival, the emperor's infant children inexplicably begin to experience grave symptoms—almost as if a curse has been cast. The curious Maomao easily solves the mystery and, to remain out of the limelight, attempts to leave an anonymous tip. Unfortunately, the dashing and perceptive eunuch Jinshi sees through it and manages to single her out. In recognition of her talent, Maomao is promoted to lady-in-waiting for the emperor's favorite concubine, Gyokuyou. As Maomao continues to remedy the numerous ailments afflicting the imperial court, her pharmaceutical expertise quickly proves indispensable.

An Orb, known only as It, is cast to Earth to be observed from afar. Capable of changing forms from beings whose reflections It captures, It first becomes a rock and then, due to the rising temperature, moss. It does not move until one snowy day, a wolf at death's door barely crosses by. When It takes the animal's form, It attains awareness of its consciousness and starts to wander with an unclear destination in mind. Soon, It comes across the wolf's master—a young boy waiting for his tribe to return from a paradise abundant with fish and fruit in the south. Although the boy is lonely, he still hopes those whom he holds dear in his memories have not forgotten him and that he will reunite with them one day. The boy wants to explore new surroundings and decides to abandon his home with It to find the paradise using the traces his tribe left behind. However, with a heavily injured body and no sight of his elder comrades, what will become of the boy? Fumetsu no Anata e illustrates the story of an immortal being experiencing humanity, meeting all types of people in many places throughout time.

Hellsing, an organization specializing in dealing with supernatural threats, is called in to eliminate a vampire that is turning the villagers of Cheddar into ghouls. To put an end to this, the leader of the organization, Sir Integra Fairbrook Wingates Hellsing, dispatches her most formidable asset: a powerful vampire known as Alucard. Armed with only a single handgun, Alucard wreaks havoc on the monsters plaguing Cheddar. However, a young police officer, Seras Victoria, gets caught up in the chaos and becomes mortally wounded as a result. Taking pity on the girl, Alucard gives her a choice: die as a human or live on as a vampire. Seras accepts his offer and begins a new life as a member of Hellsing. Though it was her decision, Seras struggles with the fact that she is no longer human. Nevertheless, she must embrace being a creature of the night soon if she wants to survive on the front lines in the fight between humans and the supernatural.