Justice, and the enforcement of it, has changed. In the 22nd century, Japan enforces the Sibyl System, an objective means of determining the threat level of each citizen by examining their mental state for signs of criminal intent, known as their Psycho-Pass. Inspectors uphold the law by subjugating, often with lethal force, anyone harboring the slightest ill-will; alongside them are Enforcers, jaded Inspectors that have become latent criminals, granted relative freedom in exchange for carrying out the Inspectors' dirty work. Into this world steps Akane Tsunemori, a young woman with an honest desire to uphold justice. However, as she works alongside veteran Enforcer Shinya Kougami, she soon learns that the Sibyl System's judgments are not as perfect as her fellow Inspectors assume. With everything she has known turned on its head, Akane wrestles with the question of what justice truly is, and whether it can be upheld through the use of a system that may already be corrupt.

Turning against his former allies and enemies alike, Eren Yeager sets a disastrous plan in motion. Under the guidance of the Beast Titan, Zeke, Eren takes extreme measures to end the ancient conflict between Marley and Eldia—but his true intentions remain a mystery. Delving deep into his family's past, Eren fights to control his own destiny. Meanwhile, the long-feuding nations of Marley and Eldia utilize both soldiers and Titans in a brutal race to eliminate the other. Reiner Braun uses his own powers in a desperate bid to hold off Eren's own militaristic force, and his fellow Eldians—children Falco Grice and Gabi Braun—struggle to survive in the unfolding chaos. Elsewhere, Eren's childhood friends Mikasa Ackerman and Armin Arlert remain imprisoned alongside Eren's former Survey Corps companions, all disturbed by Eren's monstrous transformation. Under the blind belief that Eren still secretly harbors good intentions, Mikasa and the others enter the fray in an attempt to save their friend's very soul.

The Abyss—a gaping chasm stretching down into the depths of the earth, filled with mysterious creatures and relics from a time long past. How did it come to be? What lies at the bottom? Countless brave individuals, known as Divers, have sought to solve these mysteries of the Abyss, fearlessly descending into its darkest realms. The best and bravest of the Divers, the White Whistles, are hailed as legends by those who remain on the surface. Riko, daughter of the missing White Whistle Lyza the Annihilator, aspires to become like her mother and explore the furthest reaches of the Abyss. However, just a novice Red Whistle herself, she is only permitted to roam its most upper layer. Even so, Riko has a chance encounter with a mysterious robot with the appearance of an ordinary young boy. She comes to name him Reg, and he has no recollection of the events preceding his discovery. Certain that the technology to create Reg must come from deep within the Abyss, the two decide to venture forth into the chasm to recover his memories and see the bottom of the great pit with their own eyes. However, they know not of the harsh reality that is the true existence of the Abyss.

A reunion that was supposed to spell the arrival of peaceful times is quickly shattered when Subaru Natsuki and Emilia return to Irlam village. Witnessing the devastation left behind by the calamities known as Sin Archbishops, Subaru sinks into the depths of despair as his ability to redo proves futile. As the group makes their way to the Sanctuary in search of answers, Subaru has an unexpected encounter with the Witch of Greed—Echidna. Subjected to her untamed rhythm, he is forced to dive into the spirals of the past and future. At the same time, several mysterious threats set their sights on the Sanctuary, heralding a horrific fate for the hapless people trapped within. Everlasting contracts, past sins, and unrequited love will clash and submerge into a river of blood in the second season of Re:Zero kara Hajimeru Isekai Seikatsu. Pushed to the brink of hopelessness, how long will Subaru's resolve to save his loved ones last?