After the world ran out of all traditional energy sources, only one remained—human excrement. To encourage citizens to produce as much waste as possible, the government implants a chip in the anus at birth, which provides citizens with juicybars every time it detects defecation. Juicybars are highly addictive narcotics that sometimes transform their users into mutant blue dwarfs with extreme constipation. These mutant addicts make up the Diaper Gang, those who live underground and are focused on trying to obtain juicybars. Aachi and Ssipak are two small-time crooks who steal and sell juicybars to make it on the streets. When they meet a beautiful woman who has the anal chips of every Diaper Gang member implanted in her, producing dozens of juicybars with every dump, Aachi and Ssipak strike it rich. However, with both the government and the Diaper Gang on their tails, the two struggle to protect their newfound riches.

The dying planet of Eltria is the only home of Kyrie Florian, her older sister Amitie, and her parents, who are scientists researching ways to save it. Unfortunately, the Florians must leave the planet behind to seek medical care for their father, who has contracted a lethal illness. Even with treatment, the survival rate of Kyrie's father is minuscule. Refusing to give up on her father and Eltria, Kyrie goes against the wishes of her sister and runs away from home to the peaceful planet of Earth in search of a solution. There, Kyrie and her childhood friend, Iris, pursue Earth's magical protectors—Nanoha Takamachi, Fate Testarossa, and Hayate Yagami. Nanoha and her companions possess the key to fulfilling Kyrie's objective, and the young girl must do whatever it takes to obtain it. However, it proves difficult for Kyrie, as the protectors do not easily yield to her provocation. Furthermore, Amitie soon arrives on Earth to stop her younger sister's reckless actions and bring her back home, further complicating the already delicate situation.

Daizaburo Edi-Ban, a Japanese-American, joins New York City's toughest precinct, the 34th. On his first day he is partnered up with John Estes, called Sleepy by his friends and Mad Bull by his enemies, a cop who stops crime with his own violent brand of justice. Mad Bull makes no qualms about executing common thieves with shotgun blasts if they even pose a minor threat to him or anyone around them. Mad Bull also often steals from prostitutes and does incredible amounts of property damage while fighting crime. Mad Bull's unpoliceman-like behavior often puts him in hot water with his partner Daizaburo and the 34th precinct. However, despite how reckless or illegal these acts are, a good cause is always revealed (For example, Sleepy uses the money he steals from the prostitutes to fund a venereal disease clinic and a home for battered and raped women). Perrine Valley, a police lieutenant, joins Daizaburo and Sleepy later on to help them tackle more difficult cases involving the mafia and drug-running. Mad Bull 34 is inspired by the high-action buddy cop films of the '70s and '80s. (Source: Thevinnymac)

Shizuma Origasa, once a renowned samurai in the Aizu Domain, has fallen on hard times following his home region's crushing defeat against the new imperial government. To make ends meet, Shizuma now works as a rickshaw puller in Tokyo. Meanwhile, he tirelessly searches for his missing fiancée, Sumie Kanomata, the younger sister of his close friend Gennosuke, who had entrusted Shizuma with her safety in his final moments. After foiling an assassination plot, Shizuma is hired by the police force, and he uses this opportunity to further his pursuit of Sumie. However, he soon lands in a whirlpool of political conspiracies involving government loyalists, persistent rebels, cunning courtesans, meddlesome foreigners, and even a mysterious yakuza member, Kyoushirou Shuragami.