Ever since the release of the innovative NerveGear, gamers from all around the globe have been given the opportunity to experience a completely immersive virtual reality. Sword Art Online (SAO), one of the most recent games on the console, offers a gateway into the wondrous world of Aincrad, a vivid, medieval landscape where users can do anything within the limits of imagination. With the release of this worldwide sensation, gaming has never felt more lifelike. However, the idyllic fantasy rapidly becomes a brutal nightmare when SAO's creator traps thousands of players inside the game. The log-out function has been removed, with the only method of escape involving beating all of Aincrad's one hundred increasingly difficult levels. Adding to the struggle, any in-game death becomes permanent, ending the player's life in the real world. While Kazuto Kirito Kirigaya was fortunate enough to be a beta-tester for the game, he quickly finds that despite his advantages, he cannot overcome SAO's challenges alone. Teaming up with Asuna Yuuki and other talented players, Kirito makes an effort to face the seemingly insurmountable trials head-on. But with difficult bosses and threatening dark cults impeding his progress, Kirito finds that such tasks are much easier said than done.

After a horrific alchemy experiment goes wrong in the Elric household, brothers Edward and Alphonse are left in a catastrophic new reality. Ignoring the alchemical principle banning human transmutation, the boys attempted to bring their recently deceased mother back to life. Instead, they suffered brutal personal loss: Alphonse's body disintegrated while Edward lost a leg and then sacrificed an arm to keep Alphonse's soul in the physical realm by binding it to a hulking suit of armor. The brothers are rescued by their neighbor Pinako Rockbell and her granddaughter Winry. Known as a bio-mechanical engineering prodigy, Winry creates prosthetic limbs for Edward by utilizing automail, a tough, versatile metal used in robots and combat armor. After years of training, the Elric brothers set off on a quest to restore their bodies by locating the Philosopher's Stone—a powerful gem that allows an alchemist to defy the traditional laws of Equivalent Exchange. As Edward becomes an infamous alchemist and gains the nickname Fullmetal, the boys' journey embroils them in a growing conspiracy that threatens the fate of the world.

Moments before Naruto Uzumaki's birth, a huge demon known as the Nine-Tailed Fox attacked Konohagakure, the Hidden Leaf Village, and wreaked havoc. In order to put an end to the demon's rampage, the leader of the village, the Fourth Hokage, sacrificed his life and sealed the monstrous beast inside the newborn Naruto. In the present, Naruto is a hyperactive and knuckle-headed ninja growing up within Konohagakure. Shunned because of the demon inside him, Naruto struggles to find his place in the village. His one burning desire to become the Hokage and be acknowledged by the villagers who despise him. However, while his goal leads him to unbreakable bonds with lifelong friends, it also lands him in the crosshairs of many deadly foes.

Mitsuha Miyamizu, a high school girl, yearns to live the life of a boy in the bustling city of Tokyo—a dream that stands in stark contrast to her present life in the countryside. Meanwhile in the city, Taki Tachibana lives a busy life as a high school student while juggling his part-time job and hopes for a future in architecture. One day, Mitsuha awakens in a room that is not her own and suddenly finds herself living the dream life in Tokyo—but in Taki's body! Elsewhere, Taki finds himself living Mitsuha's life in the humble countryside. In pursuit of an answer to this strange phenomenon, they begin to search for one another. Kimi no Na wa. revolves around Mitsuha and Taki's actions, which begin to have a dramatic impact on each other's lives, weaving them into a fabric held together by fate and circumstance.