The Otherworld is a vast and dangerous realm hidden from the knowledge of the common folk. It is also home to many creatures that threaten any human who dare visit it. To witness its desolate yet oddly absorbing environment, one must search for portals that could reside anywhere, from secret elevators to shrine entrances. After a fateful encounter with a horrendous Otherworld denizen, Sorawo Kamikoshi ponders whether to keep going or give up in life. Meanwhile, Toriko Nishina scours the Otherworld in hopes of finding her friend Satsuki, who she believes is lost somewhere within the realm. When the two cross paths, friendship blossoms. In order to acquire as much information about this obscure dimension, the two travel back and forth from the real world to the other. Sorawo and Toriko's bodies are soon influenced by the Otherworld, preparing them for the many horrors to come as both of them try to fulfill their goals.

The king of Slantania has officially appointed Sei Takanashi as the Holy Saint—an omnipotent maiden summoned from another world to save the kingdom. After months of relentless fighting against monsters, Sei can finally relax and continue her study at the Medicinal Flora Research Institute. Although her relationship with Albert Hawke, the commander of the Third Order of Knights, gradually blossoms, her bachelorette status attracts unwanted attention from other men—much to Albert's dismay. Moreover, Tenyuu—one of the many princes from the faraway Zaidera Empire—has taken an interest in Slantania and its powerful healing potions. Given that Sei's identity is a national secret, she must lay low in the royal palace until Tenyuu satisfies his curiosity at the institute and returns to his country. Despite his unimpressive appearance, the foreign prince is far from clueless. He has come to Slantania for a clear reason, and Sei's unique skills may just hold the answer to his cryptic research.

In the American city of Snowfield, a new Holy Grail War is about to erupt. Such ruthless confrontations pit against each other magic experts known as magi, who ascend to the status of Master by summoning Servants—heroic spirits of the past. The winner is thought to have any one of their wishes granted. However, it appears that the organization behind the present situation has merely managed to create an imperfect copy of the Third Holy Grail War. As the unusual ritual catches the attention of the Mage's Association in London, Flatt Escardos, the young apprentice of Lord El-Melloi II—a former participant of the Fourth Holy Grail War—travels to Snowfield and, to the great dismay of his teacher, joins the ranks of the Masters. In this fake conflict where the line between Masters and Servants is blurred, the different factions will have a hard time preventing the city of Snowfield from plunging into total chaos.

Specials included with the Blu-ray/DVD release of Gabriel DropOut.